Publications by authors named "Michelle Bignoumba"
Carbapenem-producing in mothers and newborns in southeast Gabon, 2022.
Front Cell Infect Microbiol
February 2024
Introduction: Infections caused by carbapenemase-producing Enterobacteriaceae (CPE) pose a significant threat, leading to severe morbidity and mortality among newborns.
Methods: This study, conducted at Franceville hospital's maternity and neonatology wards from February 22nd to June 20th, 2022, investigated the prevalence of CPE in 197 parturients and 203 newborns. Rectal swabs were taken from parturients before delivery and from newborns 30 minutes after birth.
Article Synopsis
- Malaria is a significant public health issue in Gabon, particularly in Franceville, necessitating urgent surveillance and early diagnosis for effective treatment.
- A retrospective study from 2017 to 2019 analyzed 2,518 malaria cases, revealing a prevalence of 26.1%, with young children being the most affected demographic.
- The findings indicate a need for targeted malaria control strategies in Franceville due to seasonal and gender disparities in infection rates, alongside the prominence of multiple Plasmodium species.
Article Synopsis
- Urinary tract infections (UTIs) are common in children and can lead to severe complications, particularly due to the emergence of antibiotic-resistant bacteria known as ESKAPE, which pose challenges for treatment.
- A study conducted on 508 children in South-East Gabon found a high prevalence of UTIs (59%), primarily caused by E. coli and K. pneumoniae, with various resistance profiles complicating treatment options.
- The research indicated that certain resistant strains, like DTR and CRE-E. coli, were linked to specific symptoms, highlighting the importance of understanding the antibiotic sensitivity of ESKAPE uropathogens for effective management of pediatric UTIs.
Introduction: Discomfort in women of childbearing age associated with vaginal infections, namely bacterial vaginosis (BV), aerobic vaginitis (AV), vulvovaginal candidiasis (VVC), and trichomoniasis (TV), represent a serious and ongoing gynecological complication throughout the world.
Objective: This study aimed to investigate the etiologies of vaginal infections among outpatients in south-eastern Gabon.
Methodology: A cross-sectional study was designed using participants referred directly by their treating doctor for a vaginal swab.
Article Synopsis
- - The study examined the prevalence of extended-spectrum beta-lactamases-producing Enterobacteriaceae (ESBL-PE) in Gabon by analyzing nearly 6,000 clinical samples and anal swabs from various hospitals between January 2016 and March 2018.
- - Findings revealed an ESBL-PE prevalence of 11.8% in clinical samples and 16.7% in anal swabs, with most isolates coming from urine, and the most common resistance genes identified were from the CTX-M group.
- - Although the prevalence of ESBL-PE in Gabon is currently not alarming, the study emphasizes the need for corrective measures and ongoing monitoring to prevent their spread.
Article Synopsis
- Urinary tract infections (UTIs) are a significant global health issue, leading to high rates of antibiotic use and consultations, especially in community settings.
- The study aimed to investigate the prevalence and antibiotic resistance of specific uropathogenic strains in Franceville, conducting analysis on 1,086 urine samples over a 17-month period.
- Results indicated a 29.2% prevalence of UTIs, predominantly affecting women, with notable resistance to certain antibiotics, emphasizing the importance of tailoring antibiotic usage based on local resistance patterns.