Impact of Sex on Circulating Leukocytes Composition in COPD Patients.

Purpose: Chronic obstructive pulmonary disease is characterized by chronic inflammatory response both at the lung site and at the systemic level. Abnormalities in circulating leukocytes have been reported to occur in COPD patients and have been often shown to correlate with the decline in lung function. COPD affects men and women at a virtually comparable rate, even though distinct sex specific symptoms, progression and therapeutic implications have been described.

Vaccine dose usage and wastage in the Metropolitan Region of Porto Alegre, Rio Grande do Sul, Brazil: a descriptive study, 2015-2017.

Objective: to estimate usage and wastage of multi-dose and single-dose vaccine vials in the Metropolitan Region of Porto Alegre, Rio Grande do Sul, Brazil, from 2015 to 2017.

Methods: a descriptive study was carried out based on secondary data from the National Immunization Program Information System (SIPNI) and the Strategic Health Supplies Information System (SIES).

Results: a total of 12,342 records were examined; mean wastage rate was 45.

Adolescent and youth health policies in the Portuguese-Brazilian context: specificities and approximations.

Objective: To characterize the scientific production on adolescent health policies and programs in Brazil and Portugal in the period 2010-2017.

Method: This is a literature review based on the Scoping Review method. The research guidingquestion was: "How is the scientific production on adolescent health policies and programs in Brazil and Portugal characterized?"Search was carried out in October 2017 on the BVS, EBSCO and Google Scholar platforms.

Runx2 overexpression compromises bone quality in acromegalic patients.

Acromegalic patients, characterized by excessive secretion of GH and IGF-1, show a high fracture risk but bone mineral density is a poor predictor for bone fractures in these patients. The effects of an excess of GH/IGF1 on skeleton as well as on osteogenic progenitors, i.e.

Bone histomorphometry in acromegaly patients with fragility vertebral fractures.

Context: The high risk of vertebral fractures (VFs) in acromegaly patients despite normal bone mineral density (BMD) is well known. The reasons for this paradoxical finding of skeleton fragility are poorly understood due to the limited data on bone histomorphometry in acromegaly.

Objective: This study aimed to analyze histomorphometric parameters including bone microarchitecture in acromegaly patients with VFs and normal BMD compared to normal subjects, and also to evaluate the differences between active and controlled acromegaly patients.

Clinical Features and Treatment Outcomes of Patients with Drug-Resistant and Drug-Sensitive Tuberculosis: A Historical Cohort Study in Porto Alegre, Brazil.

Purpose: To evaluate the clinical features and treatment outcomes of patients with pulmonary tuberculosis, stratified by level of drug resistance.

Methods: This was a historical cohort study based on data from the II National Anti-Tuberculosis Drug Resistance Survey (2006-2007) collected at eight participating health care facilities in Porto Alegre, southern Brazil. The cohort was followed for 3 years after the start of treatment.

Drug-resistant tuberculosis in subjects included in the Second National Survey on Antituberculosis Drug Resistance in Porto Alegre, Brazil.

Objective: To describe the prevalence of multidrug-resistant tuberculosis (MDR-TB) among tuberculosis patients in a major Brazilian city, evaluated via the Second National Survey on Antituberculosis Drug Resistance, as well as the social, demographic, and clinical characteristics of those patients.

Methods: Clinical samples were collected from tuberculosis patients seen between 2006 to 2007 at three hospitals and five primary health care clinics participating in the survey in the city of Porto Alegre, Brazil. The samples were subjected to drug susceptibility testing.

[Female condom: a possibility for autonomy in HIV-positive women].

In this article, the authors report an experience developed in the Specialized Care Sevice on STD/AIDS from Porto Alegre, where one of them works. It approaches adult women, emphasizing sexuality, reproduction and vulnerability concerning STDs, mainly HIV infection. The methodology used is a data survey starting from the return to the service in order to receive female condoms within one year.