A systematic review and meta-analysis of second-line immunosuppressants for autoimmune hepatitis treatment.

Introduction: The gold-standard treatment for autoimmune hepatitis (AIH) is a prednisone/azathioprine combination. However, subgroups of patients may be unresponsive to this treatment. The aim of this study is to evaluate the efficacy of second-line immunosuppressive therapies for AIH through a systematic review and meta-analysis in adult patients.

Comparison of removal techniques in the management of buried bumper syndrome: a retrospective cohort study of 82 patients.

Background And Study Aims: Buried bumper syndrome is an infrequent complication of percutaneous endoscopic gastrostomy (PEG) that can result in tube dysfunction, gastric perforation, bleeding, peritonitis or death. The aim of this study was to compare the efficacy of different PEG tube removal methods in the management of buried bumper syndrome in a large retrospective cohort.

Patients And Methods: From 2002 to 2013, 82 cases of buried bumper syndrome were identified from the databases of two endoscopy referral centers.