Publications by authors named "Michele Vargas Garcia"

 Mismatch negativity (MMN) represents a negative component of event-related potentials, which is mentioned by guidelines as an important tool to provide measurable data regarding the functionality of the auditory system in acoustic processing. However, the literature still lacks reliable data that can support the clinical use of this potential in the complementary diagnosis of central auditory processing (CAP) disorder (CAPD).  To analyze whether MMN assessment might be associated with the CAP behavioral test battery, as well as to assess the effects of auditory ability deficits on MMN responses in the pediatric population.

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Purpose: To seek evidence of validity and reliability for the Compressed Speech Test with Figures.

Methods: The study was subdivided into three stages: construct validation, criteria and reliability. All participants were aged between 6:00 and 8:11.

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Objective: To analyze age-related changes in the central auditory pathway in healthy elderly individuals.

Methods: A prospective, quantitative cross-sectional study. The caseload comprised 18 adults (mean age, 22.

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Purpose: To investigate the effects of antioxidant supplementation with açaí extract on the discomfort with chronic tinnitus and the relationship with the levels of anxiety and oxidative metabolism, not excluding the overlap of diseases.

Methods: Randomized, placebo-controlled clinical trial. 30 individuals participated, with an average of 50.

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Objectives: To analyze central auditory maturation in term and preterm infants during the first 3 months of life by comparing the latency and amplitude of cortical auditory-evoked potential at different frequencies.

Methods: In this study, 17 term and 18 preterm infants were examined; all had tested positive on the neonatal hearing screening test. Cortical auditory potential was investigated during the first and third months of life.

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Objectives: This study aimed to describe and compare the performance of older adults with normal hearing and hearing impairments in mismatch negativity (MMN), correlate MMN with cognitive tasks and central auditory processing (CAP), and identify normal values for MMN in older adults.

Methods: This study had 54 participants. The Montreal Cognitive Assessment (MoCA) was used to assess cognition and the random gap detection test (RGDT), dichotic digit test (DDT), and speech to noise (SN) test were used to evaluate CAP.

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 The mismatch negativity (MMN) is a long-latency auditory evoked potential related to a passive elicited auditory event.  To verify the occurrence of MMN with different stimuli, to describe reference values in normal-hearing adults with verbal and nonverbal stimuli and to compare them with each other, besides analyzing the latency, area, and amplitude regarding gender and between the ears.  Normal-hearing individuals, aged between 18 and 59 years old, participated in the study.

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 Mismatch negativity (MMN) is a long latency auditory evoked potential, represented by a negative wave, generated after the potential N1 and visualized in a resulting wave.  To identify the time of occurrence of MMN after N1, elicited with verbal and nonverbal stimuli.  Ninety individuals aged between 18 and 56 years old participated in the study, 39 of whom were male and 51 female, with normal auditory thresholds, at least 8 years of schooling, and who did not present auditory processing complaints.

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 Frequency-following response with speech stimulus (FFR-speech) is a subcortical potential that satisfactorily evaluates the processing of verbal information. However, there still are differences in the literature regarding its analysis and stimulation protocol.  To compare two stimulation protocols for the capture of FFR-speech, to identify the percentage of occurrence of the waves among them and to compare it with the specialized literature, as well as to describe the interpeaks of its waves.

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Purpose: To compare the ability to recognize sentences in silence and in noise in monolingual normal-hearing Brazilian Portuguese speakers, and bilingual speakers of Brazilian Portuguese and German, and bilingual speakers of Brazilian Portuguese and Italian, as well as to analyze the influence of age of second language acquisition on the performance of bilinguals.

Methods: 87 normal-hearing individuals aged between 18 and 55 years participated of this research. They were categorized into: Control Group, composed by 30 monolingual Brazilian Portuguese speakers; German Research Group, 31 simultaneous bilingual native speakers of Portuguese and speakers of German as a second language and; Italian Research Group, consisting of 26 successive bilinguals, native speakers of Portuguese and speakers of Italian as a second language.

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Introduction: The study of the threshold level of cortical auditory response in adults has been investigated in previous studies. Due to maturational issues, little is known about these responses in neonates. Technological advances with automatic analysis devices now allow investigation in specific populations.

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Purpose: Evaluate high-frequency auditory thresholds, seeking to compare responses between the ears, to verify the correlation between hearing level and aging and analyze frequency responses in normal hearing adults.

Methods: This is a prospective, quantitative, transversal study conducted with a convenience sample. Study participants were 60 individuals aged 18 to 58 years (mean=25.

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 The use of the speech-evoked auditory brainstem response (ABR) shows how the brainstem operates up to the subcortex in a more complex manner than when the click-evoked ABR is used.  To study the applicability of the speech-evoked ABR in adults with hearing loss.  The sample was composed of a study group of 11 subjects, with ages ranging between 18 and 59 years, and auditory thresholds within normal standards, with loss of up to 65 dB at high frequencies or up to moderately severe symmetric sensorineural hearing loss.

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Purpose: To investigate the auditory ability of selective attention in the school population and to identify reference values to the age group from seven to ten years old through the Masking Level Difference Test, and to identify if the parents' schooling, as well as the family income can influence the test results.

Methods: Thirty-one schoolchildren who match the eligibility criteria attended the study, being 20 female and 11 male. An anamnesis was conducted to question the familiar income and the schooling of the children´s parents; we also performed visual inspection of the External Acoustic Meatus, Pure Tone Audiometry, Speech Audiometry, Acoustic Immittance Measures, Dichotic Digits Test and Masking Level Difference test.

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Purpose Evaluate the auditory pathway at the brainstem and cortical levels in individuals with peripheral vestibular dysfunction. Methods The study sample was composed 19 individuals aged 20-80 years that presented exam results suggestive of Peripheral Vestibular Disorder (PVD) or Vestibular Dysfunction (VD). Participants underwent evaluation of the auditory pathway through Brainstem Auditory Evoked Potentials (BAEP) (short latency) and P1, N1, P2, N2, and P300 cortical potentials (long latency).

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 The auditory system consists of sensory structures and central connections. The evaluation of the auditory pathway at a central level can be performed through behavioral and electrophysiological tests, because they are complementary to each other and provide important information about comprehension.  To correlate the findings of speech brainstem-evoked response audiometry with the behavioral tests Random Gap Detection Test and Masking Level Difference in adults with hearing loss.

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 Computerized auditory training (CAT) has been building a good reputation in the stimulation of auditory abilities in cases of auditory processing disorder (APD).  To measure the effects of CAT in students with APD, with typical or atypical phonological acquisition, through electrophysiological and subjective measures, correlating them pre- and post-therapy.  The sample for this study includes14 children with APD, subdivided into children with APD and typical phonological acquisition (G1), and children with APD and atypical phonological acquisition (G2).

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Objective: To establish reference intervals for cognitive potential P300 latency using tone burst stimuli.

Methods: This study involved 28 participants aged between 18 and 59 years. P300 recordings were performed using a two-channel device (Masbe, Contronic).

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Introduction Long Latency Auditory Evoked Potentials (LLAEP) with speech sounds has been the subject of research, as these stimuli would be ideal to check individualś detection and discrimination. Objective The objective of this study is to compare and describe the values of latency and amplitude of cortical potentials for speech stimuli in adults with normal hearing. Methods The sample population included 30 normal hearing individuals aged between 18 and 32 years old with ontological disease and auditory processing.

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Objective: Investigate the effect of acupuncture on brain perfusion using ethyl cysteinate dimer single-photon emission computed tomography ((99m)Tc-ECD SPECT) in patients with tinnitus.

Methods: This randomized, single-blind, sham-control study examined patients (18-60 years old) with normal hearing and chronic, idiopathic, continuous tinnitus. Fifty-seven subjects were randomly assigned to true (n = 30) or sham (n = 27) acupuncture (ACP); (99m)Tc-ECD SPECT examinations were performed before and after 12 twice-weekly ACP sessions.

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Introduction: Procedures for extending the life of newborns are closely related to potential causes of hearing loss, justifying the identification and understanding of risk factors for this deficiency.

Objective: To characterize the population, analyze the frequency of risk factors for hearing loss, and assess the audiological status of infants attended in a Newborn Hearing Screening program (NHS).

Methods: This was a retrospective study that analyzed medical records of 140 patients from a neonatal intensive care unit, identifying the frequency of risk factors for hearing loss and audiological status, utilizing transient otoacoustic emissions and brainstem auditory evoked potential (BAEP).

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Introduction: Long-latency auditory evoked potentials represent the cortical activity related to attention, memory, and auditory discrimination skills. Acoustic signal processing occurs differently between verbal and nonverbal stimuli, influencing the latency and amplitude patterns.

Objective: To describe the latencies of the cortical potentials P1, N1, P2, N2, and P3, as well as P3 amplitude, with different speech stimuli and tone bursts, and to classify them in the presence and absence of these data.

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Purpose: To verify the association between the amplitude of distortion-product otoacoustic emissions (DPOAE) and biomarkers of oxidative stress (OS) in resident students of the tobacco-producing region.

Methods: Participated in the study group (SG) 21 normal-hearing students from the tobacco-producing region, and in the control group (CG) 25 normal-hearing students who did not live in the countryside. The auditory system was assessed by DPOAE and the following biomarkers: dichlorofluorescein diacetate (DCFH-DA) and micronucleus test (MN).

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Unlabelled: Tinnitus is characterized by the perception of sound in the absence of an external auditory stimulus. The network connectivity of auditory and non-auditory brain structures associated with emotion, memory and attention are functionally altered in debilitating tinnitus. Current studies suggest that tinnitus results from neuroplastic changes in the frontal and limbic temporal regions.

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