Publications by authors named "Michele Pezza"
Acne is a pathology of the pilosebaceous unit. It is characterized by a highly complex etiopathology which includes inflammation, hyperkeratinization, increased sebum production, colonization of , hyperandrogenemia, and hyperinsulinemia. This condition, together with hirsutism, androgenic alopecia, and acanthosis nigricans, are highly prevalent cutaneous manifestations of the polycystic ovary syndrome (PCOS).
View Article and Find Full Text PDFSmartphone apps may help promoting the early diagnosis of melanoma. The reliability of specialist judgment on lesions should be assessed. Hereby, we evaluated the agreement of 6 young dermatologists, after a specific training.
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- Long-term management of psoriasis is crucial but challenging; the PSO-LONG trial showed that a combination treatment of betamethasone dipropionate and calcipotriol foam, applied twice a week for a year, can reduce relapses but still needs further investigation for long-term use.
- In the ProActive Management (PAM) program, experts reached consensus on 14 out of 18 statements, recognizing the importance of proactive topical treatments to minimize relapse risk, especially for resistant disease sites or when other therapies are not suitable.
- Establishing proactive strategies in treatment guidelines is seen as vital for improving the management of mild to moderate psoriasis, while more research on patient adherence is necessary.
Combination therapy is a common approach to psoriasis, aimed at improving clinical response and minimizing the risk of side effects. The aim of this pilot randomized open-label study was to evaluate the efficacy and safety of the combination of low-dose cyclosporine (CsA) with calcipotriol-betamethasone dipropionate (CBD) ointment in the treatment of psoriasis. Sixty patients with moderate-to-severe plaque psoriasis were randomized to receive CsA, 2 mg/kg/day, combined with CBD ointment (n = 30) or CsA, at the same daily dosage, in combination with an emollient (n = 30), for 8 weeks.
View Article and Find Full Text PDFBackground: conventional antipsoriatic therapies are often administered until remission, with treatment resumed in the case of relapse, in order to reduce the likelihood of cumulative, dose-dependent toxicities. Biological agents have been safely used in continuous therapy.
Objective: to assess the use of etanercept for psoriasis in clinical practice in Italy.
Background: Specific subcutaneous immunotherapy (SCIT) with house dust mite (HDM) preparation has recently been shown to improve eczema in patients with atopic dermatitis (AD). So far, there is less data regarding efficacy and safety of specific sublingual immunotherapy (SLIT) in patients with AD.
Study Aim: To evaluate in an open non-controlled, non-randomized pilot trial the effect of SLIT with HDM allergen extracts preparation (SLITone, ALK Abellò Italy) on SCORAD in adult patients with mild-moderate AD.