Publications by authors named "Michele M Estabrook"
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Synopsis of recent research by authors named "Michele M Estabrook"
- Michele M Estabrook's research primarily focuses on the immunological responses to various bacterial pathogens, particularly involving Neisseria meningitidis and related opportunistic infections in immunocompromised patients.
- A significant part of her work has explored the mechanisms by which human antibodies and lectins, such as mannose-binding lectin, interact with bacterial structures to promote bacterial clearance through complement activation and opsonization.
- Recent findings include a case study of Aicardi-Goutières syndrome with Pneumocystis jirovecii pneumonia and the characterization of antibody responses against specific lipooligosaccharide structures, highlighting the importance of humoral immunity in combating severe bacterial infections.