Publications by authors named "Michele Fernandes"
Lack of genotoxicity of iron oxide maghemite (γ-Fe2O3) and magnetite (Fe3O4) nanoparticles to Oreochromis niloticus after acute exposures.
Genet Mol Biol
September 2024
Iron oxide nanoparticles (FeO-NPs) are widely used in scientific and technological fields. Environmental concerns have been raised about residual FeO-NPs levels as their toxicity and bioaccumulative potential are not well understood. Oreochromis niloticus were exposed to nanoparticles of γ-Fe2O3 and Fe3O4.
View Article and Find Full Text PDFArticle Synopsis
- Scientific Initiation (SI) involves students starting their scientific training under experienced researchers, but research on the experiences of these researchers is limited, prompting a systematic review to identify influencing factors and motivations.
- The study will utilize various bibliographic databases for literature search, adhering to established guidelines for systematic reviews, and will include a range of peer-reviewed articles without language restrictions.
- The findings will be categorized and presented using visual tools, and the study will assess bias through established checklists while ensuring discrepancies are resolved by a senior reviewer.
Article Synopsis
- The study focuses on understanding the quality of life (QoL) of administrative professionals in educational institutions, particularly how it has been impacted by remote versus in-person work, as well as by the COVID-19 pandemic.
- A systematic review will be conducted using five databases to gather original, peer-reviewed articles, which will be analyzed by researchers to assess the quality of evidence and risk of bias.
- The findings will be published in a peer-reviewed journal and shared at a conference, with no individual patient data involved, eliminating the need for ethical approval.
The objectives of this systematic review were to estimate the prevalence of depression and to identify the relationship between depression and quality of life (QOL) among high school and university students. Literature search was performed in the Scopus, Embase, PubMed, Scielo, CINAHL and Web of Science databases, following the PRISMA methodology. The results were presented through descriptive approaches and meta-analysis.
View Article and Find Full Text PDFThe objectives of this study were to compare the prevalence of depressive symptoms, behavioral habits, and QoL in students from two vocational-technical schools, and to determine the association of depressive symptoms with behavioral habits and quality of life (QoL) in these students during the COVID-19 pandemic. A cross-sectional survey was conducted with students attending the institution of the Brazilian Federal Network of Professional, Scientific and Technological Education. The students answered a questionnaire on sociodemographic variables, situations related to the COVID-19 pandemic, behavioral habits, QoL, and depressive symptoms.
View Article and Find Full Text PDFBack pain is a public health problem that affects adolescents and adults worldwide. However, studies on back pain present inconsistent findings in part due to the use of different instruments, especially for athletes. Therefore, the objective of this systematic review protocol was to map the existing evidence on such tools.
View Article and Find Full Text PDFThe clinical course of bronchiectasis is unpredictable, posing a challenge both in clinical practice and in research. Two mortality prediction scores, the bronchiectasis severity index (BSI) and FACED scores, have recently been developed. The aim of this study was to assess the ability of these scores to predict long-term mortality and to compare the two scores.
View Article and Find Full Text PDFUnlabelled: Oncogenic TRK fusions induce cancer cell proliferation and engage critical cancer-related downstream signaling pathways. These TRK fusions occur rarely, but in a diverse spectrum of tumor histologies. LOXO-101 is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors.
View Article and Find Full Text PDFObjective: To test the primary study hypothesis that a physician-delivered coronary heart disease risk evaluation and communication program can lower patients' predicted 10-year risk of myocardial infarction or death due to coronary heart disease by 10% within 6 months compared to usual care.
Design: Prospective, parallel group, open-label, controlled, cluster-randomized multinational trial; the study site is the unit of randomization.
Setting: Patients were recruited from 106 general practices located in nine European countries.