Publications by authors named "Michele Cevolani"
Background: Catheter-related bloodstream infections (CRBSI) represent a frequent complication of vascular catheterization, with high morbidity, mortality, and associated costs. Most infections are caused by Gram-positive bacteria; thus dalbavancin, a new long-acting lipoglicopeptide, may have a role in early patient discharge strategies optimizing treatment and reducing overall costs.
Methods: In this small pilot feasibility study, we assessed the efficacy and safety of a "single step" treatment strategy combining dalbavancin administration (1500 mg IV single dose), catheter removal, and early discharge in adult patients admitted to medical wards in a three-year period.
Article Synopsis
- - A 72-year-old man with a history of hepatitis C and hepatocellular carcinoma (HCC) experienced fatigue and a skin rash, leading to a diagnosis of dermatomyositis (DM) associated with anti-TIF1-γ antibodies, indicative of HCC recurrence.
- - Despite treatment with corticosteroids, azathioprine, and intravenous immunoglobulin, he showed only a partial response, leaving him without feasible options for HCC treatment due to poor health, resulting in best supportive care being provided.
- - The case highlights the link between anti-TIF1-γ antibodies and paraneoplastic DM in HCC, along with the tumor-related aspects of TIF1-γ, which may serve as