Publications by authors named "Michele Bedognetti"
Article Synopsis
- The study explores how mRNA vaccines for COVID-19 trigger immune responses, revealing that the first dose leads to modest immune reactions while the second dose causes stronger interferon and inflammatory responses.
- Blood samples taken at high frequency showed that both doses generated different patterns of interferon responses, indicating variations in immune reaction quality and quantity.
- The findings suggest distinct immune response patterns are associated with COVID-19 severity, emphasizing the importance of closely monitoring immune responses after vaccination.
Introduction: Accurate triage is an important first step to effectively manage the clinical treatment of severe cases in a pandemic outbreak. In the current COVID-19 global pandemic, there is a lack of reliable clinical tools to assist clinicians to perform accurate triage. Host response biomarkers have recently shown promise in risk stratification of disease progression; however, the role of these biomarkers in predicting disease progression in patients with COVID-19 is unknown.
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