Publications by authors named "Michelangelo Pianelli"
Article Synopsis
- Immunoglobulin G4-related disease (IgG4-RD) is an immune disorder that leads to organ swelling and fibrosis and can rarely occur alongside primary immune thrombocytopenia (ITP), which is marked by low platelet counts without a clear cause.
- A case study presents a 56-year-old woman with a history of ITP since 2005, who developed IgG4-RD in 2011, requiring various treatments including steroids, azathioprine, and other therapies due to relapses of ITP.
- The patient experienced some improvement with a combination of low-dose prednisone and mycophenolate, but her platelet count remains a concern, suggesting the need for further research into potential links between Ig
Article Synopsis
- Sarcoidosis is a complex disease that can affect multiple organs and may cause severe thrombocytopenia due to factors like hypersplenism and immune-related issues.
- A case of a young male with extreme thrombocytopenia and related symptoms led doctors to rule out infections and hematological disorders, yet initial treatments for immune thrombocytopenia (ITP) did not succeed.
- After trying various therapies, including Romiplostim, the patient's platelet count recovered, and further imaging raised concerns about underlying sarcoidosis as a contributing factor to his condition.
Leuk Res Rep
January 2023
Article Synopsis
- The case discusses a 78-year-old woman with severe leukocytosis and anemia who initially appeared asymptomatic and was hospitalized for a routine check-up.
- After an abdominal ultrasound showed mild splenomegaly, further examinations revealed a significant decline in her cognitive function and multiple brain lesions a week later.
- An autopsy confirmed extreme infiltration of leukemia in various organs, indicating a complex condition potentially classified as an overlap syndrome between atypical chronic myeloid leukemia (aCML) and myelodysplastic/myeloproliferative neoplasm (MDS/MPN), making diagnosis challenging.
