Publications by authors named "Michela Gaiano"
Unveiling the advantages of laparoscopic myomectomy: A comprehensive systematic review and meta-analysis of outcomes and complications compared with traditional open surgery.
Eur J Obstet Gynecol Reprod Biol
December 2024
Article Synopsis
- The study compares laparoscopic myomectomy (LM) and open myomectomy (OM) by analyzing postoperative complications, blood loss, operative time, and length of hospital stay using the Clavien-Dindo classification.
- LM showed significantly lower rates of overall postoperative complications and mean blood loss compared to OM, with an associated statistically significant shorter hospital stay.
- Additionally, while operative times were similar, the findings indicate a clear advantage for LM in terms of patient recovery and safety.
Endometriosis is a benign condition affecting women of reproductive age. A potential association with ovarian cancer has been documented. Atypical endometriosis (AE) is characterized by deviations from the typical microscopic appearance of endometriosis, including cytologic and architectural atypia.
View Article and Find Full Text PDFOvarian cancer (OC) remains a significant health challenge globally, with high mortality rates despite advancements in treatment. Emerging research suggests a potential link between OC development and genital dysbiosis, implicating alterations in the microbiome composition as a contributing factor. To investigate this correlation, a meta-analysis was conducted following PRISMA and MOOSE guidelines, involving eight studies encompassing 3504 patients.
View Article and Find Full Text PDFThe establishment of PARP inhibitors in the treatment of epithelial ovarian carcinoma (EOC) has prompt BRCA assessment at the time of diagnosis. We described our five years of experience of tumor BRCA testing, as part of a multidisciplinary workflow for the management of EOC patients. We used a BRCA next-generation sequencing (NGS) test for profiling formalin-fixed, paraffin-embedded (FFPE) EOCs of 762 consecutive patients, with a success rate of 99.
View Article and Find Full Text PDFArticle Synopsis
- Hemoperitoneum, or bleeding in the abdominal cavity, can result from trauma, tumors, gastrointestinal perforations, or less commonly, coagulopathies, with the superior epigastric artery (SEA) being a rare source of injury.
- A case study discusses a 44-year-old woman who experienced hemoperitoneum following cytoreductive surgery for ovarian cancer, where active bleeding from the SEA was identified via CT scan.
- The patient underwent coil embolization and surgical drainage to address the bleeding; despite initial success, additional embolization was needed, ultimately leading to complete resolution as confirmed by ultrasound.
Obstetrics outcomes after complete and partial molar pregnancy: Review of the literature and meta-analysis.
Eur J Obstet Gynecol Reprod Biol
April 2021
The hydatidiform mole is a rare gynecological disease rising from the trophoblastic. Post-molar pregnancies have an extremely variable course, varying from repeated abortions, stillbirths, preterm births, live births, or recurring in further molar pregnancies. Literature on obstetric outcomes following molar pregnancy is poor, often including monocentric studies, and with data collected from national databases.
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