Selenium supplementation prevents the increase in atherogenic electronegative LDL (LDL minus) in the postprandial phase.

Evidence is accumulating that postprandial phenomena play a role in atherogenesis. Dietary lipid hydroperoxides that escape from the gastrointestinal barrier can be incorporated into plasma lipoproteins, leading to a modified form of LDL (LDL minus). The present human study was designed to investigate the effect of selenium supplementation on the formation of LDL minus in the postprandial phase.