Publications by authors named "Michela Barini"
Article Synopsis
- The study evaluated frailty in patients scheduled for elective thoracic surgery, noting that while frailty is linked to poor surgical outcomes, the best assessment method is still unclear.
- Using several frailty assessment tools, it was found that 53% of the 94 patients were prefrail or frail, with the Fried frailty phenotype being the most accurate predictor of postoperative complications.
- The study concluded that recognizing frailty and related factors, like depression and muscle health, could help surgeons improve patient outcomes, suggesting further research on interventions for frail patients undergoing surgery.
Background: Our aim is to evaluate the possible persistence of lung parenchyma alterations, in patients who have recovered from Covid-19.
Design And Methods: We enrolled a cohort of 115 patients affected by Covid-19, who performed a chest CT scan in the Emergency Department and a chest CT 18 months after hospital discharge. We performed a comparison between chest CT scan 18 months after discharge and spirometric data of patients enrolled.
The National Health Systems have been severely stressed out by the COVID-19 pandemic because 14% of patients require hospitalization and oxygen support, and 5% require admission to an Intensive Care Unit (ICU). Relationship between COVID-19 prognosis and the extent of alterations on chest CT obtained by both visual and software-based quantification that expresses objective evaluations of the percentage of ventilated lung parenchyma compared to the affected one has been proven. While commercial applications for automatic medical image computing and visualization are expensive and limited in their spread, the open-source systems are characterized by not enough standardization and time-consuming troubles.
View Article and Find Full Text PDFPredictors of intubation and mortality in COVID-19 patients: a retrospective study.
J Anesth Analg Crit Care
November 2021
Background: Estimating the risk of intubation and mortality among COVID-19 patients can help clinicians triage these patients and allocate resources more efficiently. Thus, here we sought to identify the risk factors associated with intubation and intra-hospital mortality in a cohort of COVID-19 patients hospitalized due to hypoxemic acute respiratory failure (ARF).
Results: We included retrospectively a total of 187 patients admitted to the subintensive and intensive care units of the University Hospital "Maggiore della Carità" of Novara between March 1st and April 30th, 2020.
Many coronavirus disease 2019 (Covid-19) survivors show symptoms months after acute illness. The aim of this work is to describe the clinical evolution of Covid-19, one year after discharge. We performed a prospective cohort study on 238 patients previously hospitalized for Covid-19 pneumonia in 2020 who already underwent clinical follow-up 4 months post-Covid-19.
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- The study reviews the effectiveness of MRI in diagnosing acute injuries to the anterior talo-fibular ligament (ATFL), as most previous research focused on chronic injuries and symptoms.
- Seven relevant studies were analyzed, revealing that MRI has high sensitivity and specificity for diagnosing acute ATFL injuries, with pooled sensitivity at 1.0 and specificity at 0.9.
- The findings suggest that while MRI is accurate and could be beneficial for diagnosing acute cases, its high cost often prevents its use in clinical settings.
Article Synopsis
- The study focuses on understanding the varied prognosis of COVID-19 by identifying clinical and laboratory indicators that can predict poor outcomes in hospitalized patients.
- Researchers analyzed data from 664 COVID-19 patients in Northern Italy, discovering that factors like red cell distribution width (RDW), neutrophil-to-lymphocyte (NL) ratio, and platelet count are significant predictors of in-hospital mortality.
- The results suggest that using simple blood tests could help in classifying the severity of COVID-19, ultimately guiding treatment and monitoring strategies for better patient management.
Article Synopsis
- Traumatic brachial plexus injuries are serious and can be either irreparable (pre-ganglionic) or treatable (post-ganglionic) depending on the injury's nature and timely diagnosis.
- The review evaluates how effective magnetic resonance imaging (MRI) is in diagnosing post-ganglionic lesions compared to results from surgical procedures.
- Results showed that MRI has high sensitivity and specificity for identifying these injuries, establishing it as a key diagnostic tool despite some limitations.
Clinical features and natural history of coronavirus disease 2019 (COVID-19) differ widely among different countries and during different phases of the pandemia. Here, we aimed to evaluate the case fatality rate (CFR) and to identify predictors of mortality in a cohort of COVID-19 patients admitted to three hospitals of Northern Italy between March 1 and April 28, 2020. All these patients had a confirmed diagnosis of SARS-CoV-2 infection by molecular methods.
View Article and Find Full Text PDFWe describe a patient affected by Covid-19 acute respiratory distress syndrome with a cerebral nervous system vasculitis triggered by SARS-Cov-2, managed at the University hospital, in Novara, Italy in the area most impacted by the pandemic and where 749 Covid-19 positive patients were admitted from March 1st until April 25th, 2020.
View Article and Find Full Text PDFObjectives: The goal of this study was to assess chest computed tomography (CT) diagnostic accuracy in clinical practice using RT-PCR as standard of reference.
Methods: From March 4th to April 9th 2020, during the peak of the Italian COVID-19 epidemic, we enrolled a series of 773 patients that performed both non-contrast chest CT and RT-PCR with a time interval no longer than a week due to suspected SARS-CoV-2 infection. The diagnostic performance of CT was evaluated according to sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy, considering RT-PCR as the reference standard.
Background: Few biomarkers are available for early identification of pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD) in systemic sclerosis (SS) and scleroderma spectrum disorders (SSD).
Aims: To evaluate Gas6, sAxl, and sMer as biomarkers for cardiopulmonary complications of SS and SSD.
Methods: In a cross-sectional observational study, we recruited 125 consecutive patients, affected by SS and SSD and referred to a tertiary-level pulmonary hypertension outpatient clinic.
Objective The aim of this work is to evaluate the diagnostic accuracy of 0.3T sectoral MR imaging, compared with arthroscopy, for meniscal, cruciate ligaments and chondral knee lesions. Materials and Methods We conducted a retrospective study analyzing all the consecutive knees subjected to arthroscopy at our institution between January 2014 and June 2017 and preceded within 3 months by knee MR examination at our institution with 0.
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