Publications by authors named "Michela Alfiero Bordigato"

Article Synopsis
  • This study examines how moderate hyperoxia impacts lung health in newborn rats and explores whether L-citrulline can help reduce lung injury by boosting nitric oxide production.* -
  • Newborn rats exposed to high oxygen levels were treated with L-citrulline, leading to increased serum L-arginine and improvements in lung growth markers, such as vascular endothelial growth factor (VEGF), compared to untreated groups.* -
  • The findings suggest that L-citrulline treatment enhances lung development and matrix regulation in oxygen-damaged lungs, potentially offering a therapeutic strategy for similar conditions.*
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We measured circulating ADMA concentrations in a group of very premature newborns at birth and during the first week of life. ADMA levels resulted significantly higher in infants born to mothers with histologic chorioamnionitis than in infants delivered for other maternal or fetal indications, both at birth and through the first week of life. We speculate that ADMA might be involved in the complex biological events associated with fetal exposure to chorioamnionitis.

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