Publications by authors named "Michel Olmer"
Article Synopsis
- This study examines oxidative stress markers in hemodialysis patients, focusing on regional differences and the impact of vitamin E-coated membranes.
- Baseline measurements of LDL oxidizability were taken from patients at five facilities, followed by a crossover trial comparing vitamin E membranes to standard membranes over several months.
- Results revealed regional variations in LDL oxidizability, but no significant benefits from using vitamin E membranes in improving these oxidative stress markers.
Background: Induction therapy with antithymocyte globulin (ATG) reduces the incidence of acute rejection after transplantation. A study was undertaken to assess the efficacy and safety of ATG induction on tacrolimus-based and cyclosporine A (CsA)-based therapies compared with immediate tacrolimus triple therapy in kidney transplant recipients.
Methods: In a 6-month, open-label, randomized, prospective study conducted in 30 European centers, 555 renal transplant patients were randomly assigned to tacrolimus triple therapy (Tac triple, n=185), ATG induction with tacrolimus (ATG-Tac, n=186), or ATG induction with CsA microemulsion (ATG-CsA, n=184); all were combined with azathioprine and corticosteroids.