Effective Antimalarial Activities of α-Hydroxy Diynes Isolated from Ongokea gore.

Three diynes, octadec-17-ene-9,11-diynoate ethyl (1: ), 8-hydroxy-octadeca-13,17-diene-9,11-diynoate ethyl (2: ), and 8-hydroxy-octadec-13-ene-9,11-diynoate ethyl (3: ), were isolated from seed oil. The structure assignment of these three compounds was based according to chemical and spectroscopic data. They were screened against , the parasite that causes malaria.