Pristinamycin production using and date sirup as substrate-process modeling, optimization, and scale-up.

Pristinamycin biosynthesis using and date sirup (DS) as substrates was optimized before scale-up. DS was filter sterilized as heat sterilization primes Maillard reactions having negative effects on antibiotic production. Multilinear regression modeling (MLR) predicted optimum medium composition, specifying components with positive and negative effects on production.

, a natural overproducer of succinic acid?

is well known as an important industrial amino acid producer. For a few years, its ability to produce organic acids, under micro-aerobic or anaerobic conditions was demonstrated. This study is focused on the identification of the culture parameters influencing the organic acids production and, in particular, the succinate production, by this bacterium.

Pilot-scale biomethanation of cattle manure using dense membranes.

This study aimed at studying the biomethanation process using a 100 L pilot-scale digester equipped with a dense membrane for hydrogen injection. Hydrogen mass transfer was characterized and the impact of hydrogen flowrate, agitation rate and of the co-injection of CO, on biogas production and composition, was precisely studied. A linear relationship between H flowrate and the CO and CH rates in biogas was found but no impact on biogas flowrate was shown.

Impact of shear stress and impeller design on the production of biogas in anaerobic digesters.

Today, intensification of anaerobic digestion is still a scientific and technical challenge. The present study proposed combined experimental and computational fluid dynamics simulations to characterize the impact of shear stress and impeller design on the biogas production after sequential additions of substrate. Liquid phase (cattle manure digestate) rheological law was experimentally determined and input in numerical simulations.

Lactate production as representative of the fermentation potential of Corynebacterium glutamicum 2262 in a one-step process.

The fermentative properties of thermo-sensitive strain Corynebacterium glutamicum 2262 were investigated in processes coupling aerobic cell growth and the anaerobic fermentation phase. In particular, the influence of two modes of fermentation on the production of lactate, the fermentation product model, was studied. In both processes, lactate was produced in significant amount, 27 g/L in batch culture, and up to 55.

Joint effect of nitrogen sources and B vitamin supplementation of date juice on lactic acid production by Lactobacillus casei subsp. rhamnosus.

The use of date juice as a substrate for lactic acid production was investigated. Various nitrogen sources were compared with yeast extract for efficient lactic acid production by Lactobacillus casei subsp. rhamnosus.