Publications by authors named "Michel Fayad"
Four noninstitutionalized patients, 4 months - 51 years old, presented out of 421 patients with epilepsy seen within a period of 2 years with serious symptoms of vitamin D deficiency secondary to chronic antiepileptic drug therapy. Presenting symptoms included exacerbation of seizure activity, status epilepticus, carpopedal spasms, fractures, osteomalacia, and rickets. All had low serum calcium and low vitamin D levels.
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- This study aimed to evaluate the effectiveness and safety of lamotrigine in infants under one year with severe seizures, specifically looking at its impact over three months.
- It found that both partial seizures and infantile spasms significantly decreased in frequency after treatment, along with observable changes in the drug's clearance based on the infants' age.
- Overall, lamotrigine was deemed effective and well tolerated in young infants, though its dosage and effects vary with age, highlighting the importance of adjusting treatment as the child grows.
We administered 2 gm/kg of intravenous gamma globulin (IVIG) to each of five consecutive patients with Landau-Kleffner syndrome, over 4 days. We compared the 1-month baseline to that following IVIG using a severity score assessing speech, comprehension, behavior, seizures, and electroencephalography. There was a significant drop in this score after IVIG (P = 0.
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