Publications by authors named "Michel El Khoury"

Article Synopsis
  • Hemophilia, a bleeding disorder, poses higher risks for adverse outcomes and longer hospital stays for patients undergoing percutaneous coronary intervention (PCI) due to acute coronary syndrome (ACS).
  • A study using data from the Nationwide Inpatient Sample Database revealed that individuals with hemophilia had significantly higher rates of gastrointestinal bleeding, hemorrhagic stroke, and retroperitoneal hemorrhage compared to those without the condition.
  • The findings stress the importance of proper management of coagulation factors and collaboration between cardiologists and hematologists to improve patient outcomes in this vulnerable population.
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Article Synopsis
  • Inflammatory bowel disease (IBD) is a chronic condition affecting the gastrointestinal tract, and biologic drugs are commonly used to manage inflammation by targeting the immune system.
  • Recent research indicates a possible connection between these biologic drugs and a higher risk of kidney stones (nephrolithiasis), prompting further investigation into this link.
  • The study analyzed data from 22,895 patients, revealing that those treated with Vedolizumab had a 31% higher likelihood of developing nephrolithiasis, especially when using multiple biologic medications.
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Papillary muscle rupture (PMR) is a rare complication of myocardial infarction. Its incidence has been decreasing nowadays because of improved early revascularization techniques. When it occurs, surgical treatment is the only therapeutic lifesaving approach.

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Coronary artery aneurysms (CAAs) are rare, with giant CAAs being even rarer. The precise pathophysiology of this phenomenon is still unknown. CAAs are seldom reported life-threatening abnormalities of the cardiovascular system.

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Acute coronary artery disease represents the leading cause of death worldwide. Some studies have shown that coagulation disorders can play a protective role against ischemic heart disease, presumably due to hypocoagulable state and decrease thrombin formation. However, autopsy reports showed atherosclerotic lesions in some patients with hemophilia.

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