Psychological distress and health-related quality of life in patients after hospitalization during the COVID-19 pandemic: A single-center, observational study.

Introduction: Illnesses requiring hospitalization are known to negatively impact psychological well-being and health-related quality of life (HRQoL) after discharge. The impact of hospitalization during the Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) pandemic on psychological well-being and health-related quality of life is expected to be higher due to the exceptional circumstances within and outside the hospital during the pandemic surge. The objective of this study was to quantify psychological distress up to three months after discharge in patients hospitalized during the first coronavirus disease 2019 (COVID-19) pandemic wave.

Microvascular perfusion as a target for fluid resuscitation in experimental circulatory shock.

Objectives: To study regional perfusion during experimental endotoxemic and obstructive shock and compare the effect of initial cardiac output-targeted fluid resuscitation with optimal cardiac output-targeted resuscitation on different peripheral tissues.

Design: Controlled experimental study.

Setting: University-affiliated research laboratory.

Peripheral vasoconstriction influences thenar oxygen saturation as measured by near-infrared spectroscopy.

Purpose: Near-infrared spectroscopy has been used as a noninvasive monitoring tool for tissue oxygen saturation (StO(2)) in acutely ill patients. This study aimed to investigate whether local vasoconstriction induced by body surface cooling significantly influences thenar StO(2) as measured by InSpectra model 650.

Methods: Eight healthy individuals (age 26 ± 6 years) participated in the study.