Publications by authors named "Micheal Fu"

Article Synopsis
  • The study investigates how digoxin affects patients with heart failure with reduced ejection fraction (HFrEF) in China, focusing on its interaction with atrial fibrillation and guideline-recommended treatments.
  • A total of 882 patients were analyzed, with findings showing that those using digoxin had significantly higher all-cause mortality and re-hospitalization rates compared to those not using it, despite similar heart failure-specific outcomes.
  • The conclusions indicate that digoxin is linked to an increased risk of overall mortality and re-hospitalization in HFrEF patients, regardless of other treatments or heart rhythms.
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Background: Although a large number of studies on heart failure with reduced ejection fraction (HFrEF) have found that anemia and renal dysfunction (RD) independently predicted poor outcomes, there are still few reports on patients with heart failure with preserved ejection fraction (HFpEF).

Methods: Clinical data of HFpEF patients registered in the China National Heart Failure Registration Study (CN-HF) were evaluated and the clinical features of patients with or without anemia/RD were compared to explore the impact of anemia and RD on all-cause mortality and all-cause re-hospitalization.

Results: 1604 patients with HFpEF were enrolled, the prevalence of anemia was 51.

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Article Synopsis
  • * Results showed that while both treatments lowered blood pressure, candesartan was more effective than imidapril in reducing systolic blood pressure, especially in patients with anti-AT1 receptor autoantibodies.
  • * However, no correlation was found between the level of these autoantibodies and the treatment's effectiveness, and both treatment regimens yielded similar outcomes in patients without the autoantibodies.
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