Association between squamous cell carcinoma of the head and neck and serum folate and homocysteine.

Unlabelled: The aim of this study was to evaluate the serum levels of folate and homocysteine in patients with squamous cell carcinoma of the head and neck (SCCHN) and to correlate them with the clinical stage. An attempt was made to associate the results with the effects of smoking.

Materials And Methods: Serum levels of folate and homocysteine were measured in 150 patients with histologically-proven SCCHN before any treatment and in 150 healthy volunteers (77 smokers and 73 nonsmokers).