Study of genetic and epigenetic alterations in urine samples as diagnostic markers for prostate cancer.

Background: Early diagnosis of prostate cancer and identification of new prognostic factors remain main issues in prostate cancer research. In this study, we sought to test a panel of cancer-specific markers in urine samples as an aid for early cancer diagnosis.

Materials And Methods: Sedimented urine samples of 66 candidates for needle biopsy were tested.