Publications by authors named "Michala Burges"
To assess the frequency of torticollis as a presenting symptom of pediatric CNS tumors and its impact on pre-diagnostic symptom intervals (PSIs) and patient outcomes. We performed a systematic review of studies reporting torticollis in children with various CNS tumors. We searched PubMed for studies published from January 1972 to March 2021 in English.
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- The study aims to assess how presenting features, tumor size, and treatment methods impact the risk of metastatic death in patients with advanced intraocular retinoblastoma (RB) based on a large international data set.
- A total of 1,841 patients were evaluated, categorized according to AJCC standards for tumor size, with treatment options including enucleation and various chemotherapy approaches leading to different survival outcomes.
- Results showed a significant correlation between tumor category and mortality risk, with higher risks linked to larger tumor stages (cT3) and specific complications, while primary enucleation yielded the best survival rates compared to other treatment modalities.
Purpose: To determine the value of clinical features for advanced intraocular retinoblastoma as defined by the eighth edition of the American Joint Committee on Cancer (AJCC) cT3 category and AJCC Ophthalmic Oncology Task Force (OOTF) Size Groups to predict the high-risk pathologic features.
Design: International, multicenter, registry-based retrospective case series.
Participants: Eighteen ophthalmic oncology centers from 13 countries over 6 continents shared evaluations of 942 eyes enucleated as primary treatment for AJCC cT3 and, for comparison, cT2 retinoblastoma.
Aim: To investigate whether the American Joint Committee on Cancer (AJCC) clinical category cT2b needs to be subclassified by the type and distribution of retinoblastoma (RB) seeding.
Methods: Multicentre, international registry-based data were collected from RB centres enrolled between January 2001 and December 2013. 1054 RB eyes with vitreous or subretinal seeds from 18 ophthalmic oncology centres, in 13 countries within six continents were analysed.
Purpose: We aimed to evaluate the capacity to treat retinoblastoma in the Middle East, North Africa, and West Asia region.
Methods: A Web-based assessment that investigated retinoblastoma-related pediatric oncology and ophthalmology infrastructure and associated capacity at member institutions of the Pediatric Oncology East and Mediterranean group was distributed. Data were analyzed in terms of availability, location, and confidence of use for each resource needed for the management of retinoblastoma.
Purpose: To compare metastasis-related mortality, local treatment failure, and globe salvage after retinoblastoma in countries with different national income levels.
Design: International, multicenter, registry-based retrospective case series.
Participants: Two thousand one hundred ninety patients, 18 ophthalmic oncology centers, and 13 countries on 6 continents.
Purpose: To evaluate the ability of the American Joint Committee on Cancer (AJCC) 8th edition to predict local tumor control and globe salvage for children with retinoblastoma (RB).
Design: International, multicenter, registry-based retrospective case series.
Participants: A total of 2854 eyes of 2097 patients from 18 ophthalmic oncology centers from 13 countries over 6 continents.