The impact of the size of the energy deficit on the rate of body weight in 6 months and willingness to continue reduction program conducted online-An intervention study.

Overweight and obesity are among the most serious public health problems, making new methods for their prevention, as well as treatment, constantly being sought. This study was designed as a 6 month intervention study. The main objective was to evaluate the effect of an energy deficit (10%, 20%, and 25%-groups D10, D20, and D25, respectively) on the rate of weight loss and waist and hip circumferences.

Effect of Age and Gender on the Efficacy of a 12-Month Body Weight Reduction Program Conducted Online-A Prospective Cohort Study.

Overweight and obesity are a cause of many non-communicable diseases leading to an increased risk of death. There are many programs aimed at weight reduction, but few publications have evaluated their effectiveness according to the gender and age of the subjects. The purpose of this study is to evaluate the effects of age and gender on weight loss outcomes in subjects participating in a 12-month online weight loss program.

Effectiveness of a 12-Month Online Weight Reduction Program in Cohorts with Different Baseline BMI-A Prospective Cohort Study.

The purpose of this article was to answer the question of whether people who want to reduce their body weight can achieve different results depending on their baseline BMI and whether the rate of weight loss is constant over the months of intervention. The study included 400 individuals aged 19 to 55 years with a mean BMI of 31.83 ± 4.

The effect of high-fat versus high-carb diet on body composition in strength-trained males.

Low-fat, high-carb (LFHC) and low-carb, high-fat (LCHF) diets change body composition as a consequence of the reduction of body fat of overweight persons. The aim of this study is the assessment of the impact of LFHC and LCHF diets on body composition of men of a healthy body mass who do strength sports while maintaining the appropriate calorific value in a diet and protein intake. The research involved 55 men aged 19-35, with an average BMI of 24.

The Combination of a Diversified Intake of Carbohydrates and Fats and Supplementation of Vitamin D in a Diet Does Not Affect the Levels of Hormones (Testosterone, Estradiol, and Cortisol) in Men Practicing Strength Training for the Duration of 12 Weeks.

This study aims to verify the extent to which a diversification of carbohydrates and fats intake in a diet, together with the reduction in vitamin D deficiency, impact the levels of hormones (testosterone, estradiol, cortisol) and Sex Hormone Binding Globulin (SHGB) in men doing strength training. The research involved 55 men aged 19-35. The participants were divided into two groups following two interventional diets for 12 weeks: high-fat diet (LCHF) or high-carb diet (LFHC), which were applied to satisfy the caloric requirements of each participant.

The causes of adverse changes of testosterone levels in men.

Introduction: As men age, progressive testosterone deficiency syndrome becomes an increasingly common problem. However, the decreased testosterone levels are not only the result of advanced age.

Areas Covered: PubMed search of published data on testosterone, nutritional deficiency, stress, sleep, and obesity.

The Assessment of the Supply of Calcium and Vitamin D in the Diet of Women Regularly Practicing Sport.

Introduction: The appropriate intake of calcium and vitamin D in women's diet is significant for a proper maintenance of the skeletal system.

Research Aim: The aim of the research was to assess the calcium and vitamin D supply in a diet among women regularly practicing sport.

Methodology: The research was completed by 593 women at the age of 18-50 (median 25) who played sports regularly (at least 2 times a week).

Age at onset of obesity, transcription factor 7-like 2 (TCF7L2) rs7903146 polymorphism, adiponectin levels and the risk of type 2 diabetes in obese patients.

Introduction: Interaction between obesity and genetic factors involved in the regulatory pathways of glucose homeostasis may play a significant role in diabetes development in the obese. The aim of this study was to investigate the associations between the TCF7L2 rs7903146 polymorphism, adiponectin levels, age at onset of obesity and the occurrence of type 2 diabetes (T2D) in a sample of obese Polish adults.

Material And Methods: A total of 474 unrelated obese subjects were included in this study.

Association between Fok I vitamin D receptor gene (VDR) polymorphism and impulsivity in alcohol-dependent patients.

Vitamin D appears to have an important role in the modulation of the central nervous system. Vitamin D exerts its biological effects through its interaction with the vitamin D receptor (VDR). Located on chromosome 12 (12q13.

Vitamin D and the central nervous system.

Vitamin D is formed in human epithelial cells via photochemical synthesis and is also acquired from dietary sources. The so-called classical effect of this vitamin involves the regulation of calcium homeostasis and bone metabolism. Apart from this, non-classical effects of vitamin D have recently gained renewed attention.

Serotonin 2A receptor gene (HTR2A) polymorphism in alcohol-dependent patients.

Background: The serotonergic (5-HT) dysfunction has been frequently described in subjects with alcohol dependence (AD). In the present study, a potential relationship between T102C polymorphism in the 5-HT receptor subtype 2Agene (HTR2A) and alcohol dependence was examined.

Methods: Genotypes were analyzed in 150 AD patients diagnosed with DSM-IV criteria and in 80 healthy controls.