Discrepancies between ALK protein disruption and occurrence of gene rearrangement in Polish NSCLC patients.

Background: Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor () mutations or anaplastic lymphoma kinase () rearrangement are predisposed to molecularly targeted therapies. Proper diagnostic is crucial for quick and correct patients qualification to optimal treatment method. Genetic tests to detect predictive factors could be performed sequentially.