Non-Hermitian polariton-photon coupling in a perovskite open microcavity.

Exploring the non-Hermitian properties of semiconductor materials for optical applications is at the forefront of photonic research. However, the selection of appropriate systems to implement such photonic devices remains a topic of debate. In this work, we demonstrate that a perovskite crystal, characterized by its easy and low-cost manufacturing, when placed between two distributed Bragg reflectors with an air gap, can form a natural double microcavity.

Predesigned perovskite crystal waveguides for room-temperature exciton-polariton condensation and edge lasing.

Perovskite crystals-with their exceptional nonlinear optical properties, lasing and waveguiding capabilities-offer a promising platform for integrated photonic circuitry within the strong-coupling regime at room temperature. Here we demonstrate a versatile template-assisted method to efficiently fabricate large-scale waveguiding perovskite crystals of arbitrarily predefined geometry such as microwires, couplers and splitters. We non-resonantly stimulate a condensate of waveguided exciton-polaritons resulting in bright polariton lasing from the transverse interfaces and corners of our perovskite microstructures.

A randomized crossover comparison of the bébé VieScope and direct laryngoscope for pediatric airway management by nurses in medical simulation settings.

Background: Airway management in life-threatening emergencies is essential for children, and endotracheal intubation is the gold standard. It protects against regurgitation and enables mechanical ventilation. New types of airway management equipment are being developed and implemented to meet the needs of medical personnel.

Prediction value of soluble urokinase plasminogen activator receptor (suPAR) in COVID-19 patients - a systematic review and meta-analysis.

Introduction And Objective: In COVID-19, the rapid prediction of the severity of a patient's condition using modern biomarkers can accelerate the implementation of appropriate therapy, and thus improve the patient's prognosis.

Material And Methods: A meta-analysis was conducted of data available in the literature on the differences in baseline suPAR blood concentration between patients (1) who tested positive and negative for COVID-19, (2) who had severe and non-severe COVID-19, and (3) COVID-19 survivors and non-survivors.

Results: SuPAR levels in SARS-CoV-2 negative and positive patients varied and amounted to 3.

Prognostic Performance of Cystatin C in COVID-19: A Systematic Review and Meta-Analysis.

Cystatin C is a specific biomarker of kidney function. We perform this meta-analysis to determine the association of Cystatin C with the COVID-19 severity. In this systematic review and meta-analysis, we searched PubMed, EMBASE, Cochrane library, and Web of Science for studies published until 2nd September 2022 that reported associations between Cystatin C levels and COVID-19 severity.

Initial Evaluation of Uroplakins UPIIIa and UPII in Selected Benign Urological Diseases.

Background: Uroplakins (UPs) are glycoproteins that play a specific role in the structure and function of the urothelium. Disorders which affect the normal expression of UPs are associated with the pathogenesis of infections and neoplasms of the urinary tract, primary vesicoureteral reflux, hydronephrosis and renal dysfunction. The appearance of uroplakins in the urine and/or plasma may be of potential importance in the detection of urinary tract dysfunction.

Realizing Optical Persistent Spin Helix and Stern-Gerlach Deflection in an Anisotropic Liquid Crystal Microcavity.

Spin-orbit interactions which couple the spin of a particle with its momentum degrees of freedom lie at the center of spintronic applications. Of special interest in semiconductor physics are Rashba and Dresselhaus spin-orbit coupling. When equal in strength, the Rashba and Dresselhaus fields result in SU(2) spin rotation symmetry and emergence of the persistent spin helix only investigated for charge carriers in semiconductor quantum wells.

Neuromorphic Binarized Polariton Networks.

The rapid development of artificial neural networks and applied artificial intelligence has led to many applications. However, current software implementation of neural networks is severely limited in terms of performance and energy efficiency. It is believed that further progress requires the development of neuromorphic systems, in which hardware directly mimics the neuronal network structure of a human brain.

The Dependence between Urinary Levels of Angiogenesis Factors, 8-Iso-prostaglandin F2, -Synuclein, and Interleukin-13 in Patients with Bladder Cancer: A Pilot Study.

During the last decade, a significant increase in the incidence of bladder cancer (BC) has been observed. Angiogenesis plays a key role in the process of tumor growth and metastasis. Additionally, the participation of oxidative stress and chronic inflammation in BC pathogenesis is indicated.

Reconstructing Quantum States With Quantum Reservoir Networks.

Reconstructing quantum states is an important task for various emerging quantum technologies. The process of reconstructing the density matrix of a quantum state is known as quantum state tomography. Conventionally, tomography of arbitrary quantum states is challenging as the paradigm of efficient protocols has remained in applying specific techniques for different types of quantum states.

Polaritonic Neuromorphic Computing Outperforms Linear Classifiers.

Machine learning software applications are ubiquitous in many fields of science and society for their outstanding capability to solve computationally vast problems like the recognition of patterns and regularities in big data sets. In spite of these impressive achievements, such processors are still based on the so-called von Neumann architecture, which is a bottleneck for faster and power-efficient neuromorphic computation. Therefore, one of the main goals of research is to conceive physical realizations of artificial neural networks capable of performing fully parallel and ultrafast operations.

Engineering spin-orbit synthetic Hamiltonians in liquid-crystal optical cavities.

Spin-orbit interactions lead to distinctive functionalities in photonic systems. They exploit the analogy between the quantum mechanical description of a complex electronic spin-orbit system and synthetic Hamiltonians derived for the propagation of electromagnetic waves in dedicated spatial structures. We realize an artificial Rashba-Dresselhaus spin-orbit interaction in a liquid crystal-filled optical cavity.

Chemical Synthesis of Oligoribonucleotide (ASL of tRNA T. brucei) Containing a Recently Discovered Cyclic Form of 2-Methylthio-N -threonylcarbamoyladenosine (ms ct A).

The synthesis of the protected form of 2-methylthio-N -threonylcarbamoyl adenosine (ms t A) was developed starting from adenosine or guanosine by using the optimized carbamate method and, for the first time, an isocyanate route. The hypermodified nucleoside was subsequently transformed into the protected ms t A-phosphoramidite monomer and used in a large-scale synthesis of the precursor 17nt ms t A-oligonucleotide (the anticodon stem and loop fragment of tRNA from T. brucei).

Are There Differences in Toxicity and Efficacy between Various Bacillus Calmette-Guerin Strains in Bladder Cancer Patients? Analysis of 844 Patients.

Purpose: To evaluate if there are differences in toxicity and efficacy between different Bacillus Calmette-Guerin (BCG) stains used for intravesical immunotherapy in patients with non-muscle invasive bladder cancer.

Methods: We retrospectively analysed a group of 844 patients who received TICE, RIVM and Moreau BCG strains. The allocation of the strain to each patient was random, stemming from differences in supply and distribution.

Spin polarized semimagnetic exciton-polariton condensate in magnetic field.

Owing to their integer spin, exciton-polaritons in microcavities can be used for observation of non-equilibrium Bose-Einstein condensation in solid state. However, spin-related phenomena of such condensates are difficult to explore due to the relatively small Zeeman effect of standard semiconductor microcavity systems and the strong tendency to sustain an equal population of two spin components, which precludes the observation of condensates with a well defined spin projection along the axis of the system. The enhancement of the Zeeman splitting can be achieved by introducing magnetic ions to the quantum wells, and consequently forming semimagnetic polaritons.

Creation of stable dark and anti-dark solitons in polariton dyad.

By designing an appropriate defect potential in a nonresonantly pumped exciton-polariton condensate, the polariton dyad consisting of two spatially separated condensates with phase locking can be realized. We use the phase coupling of the polariton dyad to investigate the existence of both dark and anti-dark solitons in the condensates. Surprisingly, these dissipative solitons appear to be stable and are not affected by the noise both from the initial condition and from the propagation.

Superluminal X-waves in a polariton quantum fluid.

In this work, we experimentally demonstrate for the first time the spontaneous generation of two-dimensional exciton-polariton X-waves. X-waves belong to the family of localized packets that can sustain their shape without spreading, even in the linear regime. This allows the wavepacket to maintain its shape and size for very low densities and very long times compared to soliton waves, which always necessitate a nonlinearity to compensate the diffusion.

Insight into lipophilicity of deoxyribonucleoside‑boron cluster conjugates.

Lipophilicity was investigated for 20 2'-deoxyribonucleoside derivatives modified with electron-neutral 1,2-dicarba-closo-dodecaborane, 1,12-dicarba-closo-dodecaborane, 7,8-dicarba-nido-undecaborate anion, and metallacarborane containing Co, Fe, or Cr. The partition coefficient (P) for neutral conjugates and the distribution coefficient (D) for ionic compounds were determined as a lipophilicity descriptor using a shake-flask method. All modified nucleosides had P/D values higher than those of an appropriate unmodified 2'-closo-dodecaborane and metallacarborane was found to be three orders of magnitude higher than that of its unmodified counterpart.

Calcium preparations do not inhibit allergic reactions: a randomized controlled trial.

INTRODUCTION Massive consumption of dietary supplements, including vitamins and minerals, has recently become a serious health issue in Europe. Their use may negatively affect the pharmacological activity of various medications, including antiallergic drugs. Calcium preparations are commonly used in some European countries as a popular remedy for allergy‑related skin reactions, such as itching, erythema, and wheals, as well as insect bites.

Efficient conversion of N-threonylcarbamoyladenosine (tA) into a tRNA native hydantoin cyclic form (ctA) performed at nucleoside and oligoribonucleotide levels.

A tA nucleoside was efficiently and stereospecifically transformed into a hydantoin cyclic form of N-l-threonylcarbamoyladenosine (ctA) by the use of polymer bounded carbodiimide (EDC-P) and HOBt. The procedure was successfully applied for a post-synthetic conversion of tA-containing RNA 17-mers (of the sequences of anticodon stem and loop (ASL) fragments of S. pombe tRNA and E.

Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs.

Transfer RNA modifications play pivotal roles in protein synthesis. N6-threonylcarbamoyladenosine (t6A) and its derivatives are modifications found at position 37, 3΄-adjacent to the anticodon, in tRNAs responsible for ANN codons. These modifications are universally conserved in all domains of life.

A hydantoin isoform of cyclic N6-threonylcarbamoyladenosine (ct6A) is present in tRNAs.

N6-Threonylcarbamoyladenosine (t6A) and its derivatives are universally conserved modified nucleosides found at position 37, 3΄ adjacent to the anticodon in tRNAs responsible for ANN codons. These modifications have pleiotropic functions of tRNAs in decoding and protein synthesis. In certain species of bacteria, fungi, plants and protists, t6A is further modified to the cyclic t6A (ct6A) via dehydration catalyzed by TcdA.

Urological complications after renal transplantation - a single centre experience.

Introduction: Urological complications after renal transplantation occur in between 2.5% and 30% of all graft recipients. The aim of the study was to present 7 years of experience in urological treatment of patients with a transplanted kidney.