Publications by authors named "Michal Kuzemczak"
Recent randomized clinical trials (RCTs) of STEMI patients with multi-vessel disease (MVD) reported potential superiority of immediate (ICR) vs. staged complete revascularization (SCR). Inherently, the risk of procedural MI is less likely to be detected in ICR patients, and this may have influenced the results.
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- Contrast-induced encephalopathy (CIE) is a rare but serious complication after coronary angiography, often presenting as transient cortical blindness; however, this case reports the first instance of CIE accompanied by visual and auditory hallucinations.
- An 80-year-old female patient experienced confusion and hallucinations following an elective coronary procedure, after complications were encountered during the angiography; stroke was initially suspected but ruled out through MRI.
- The patient was diagnosed with CIE and treated with sedation and quetiapine for her hallucinations, ultimately leading to the resolution of her symptoms within five days.
Background: The role of intra-coronary imaging in patients with stent failure undergoing intravascular lithotripsy (IVL) is unclear. We aimed to assess clinical outcomes in patients undergoing IVL treatment for stent failure stratified according to the use of intra-coronary imaging and lesion complexity.
Methods: This is a pre-specified subgroup analysis of patients who were included in the coronary intravascular lithotripsy in patients with stent failure (COIL) registry (international multi-centre study assessing IVL treatment for stent failure in 6 European centres).
Article Synopsis
- Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) enhance outcomes in percutaneous coronary interventions (PCIs) for certain patients.
- A study analyzed data from 6,522 rotational atherectomy (RA-PCI) procedures performed between 2014 and 2021 to assess whether IVUS or OCT improves successful revascularization rates.
- Results indicated that using these imaging techniques led to a significantly higher likelihood of achieving optimal blood flow post-procedure (TIMI 3 flow), with IVUS and OCT increasing success rates by approximately 67% and 66%, respectively.
Although rotational atherectomy (RA) and intravascular lithotripsy (IVL) have been proved to be effective for calcified de novo coronary lesions, their use in patients with in-stent restenosis (ISR) is still controversial. No comparison of these techniques in patients with ISR has been published so far. We sought to evaluate safety and feasibility of RA and IVL in patients with calcified ISR.
View Article and Find Full Text PDFBackground: Intravascular lithotripsy (IVL) has been demonstrated to be an effective treatment of calcified de novo coronary lesions. Safety data on the use of IVL within stented segments are lacking. We sought to evaluate the safety, feasibility, and long-term outcomes of IVL in patients with stent failure.
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- - The study investigates a new treatment method using platelet-rich plasma hydrogel to help restore heart function in patients suffering from chronic heart failure after a heart attack, using a minimally invasive technique called NOGA.
- - Researchers conducted experiments on pigs, finding that those treated with the hydrogel showed significant improvements in heart parameters, such as reduced scar tissue and better heart function, compared to those who did not receive the treatment.
- - The results suggest that this hydrogel-based therapy has real potential for translating into human clinical applications, warranting further research and trials to explore its use in standard clinical practice.
Background: It is unclear whether more effective forms of thrombus removal than current aspiration catheters would lead to improved outcomes. We sought to evaluate the prognostic role of residual thrombus burden (rTB), after manual thrombectomy, in patients undergoing primary percutaneous coronary intervention with routine manual thrombectomy in the TOTAL trial (Thrombectomy Versus PCI Alone).
Methods: This is a single-arm analysis of patients from the TOTAL trial who underwent routine manual aspiration thrombectomy.
Background: Inflammation is increasingly recognized as a target to reduce residual cardiovascular risk. Colchicine is an anti-inflammatory drug that was associated with improved cardiovascular outcomes. However, its effect on stroke reduction was not consistent across studies.
View Article and Find Full Text PDFBackground And Objectives: Whether the anti-inflammatory drug colchicine has a differential treatment effect according to diabetes mellitus status in patients with coronary artery disease has never been studied. Therefore, the aim of the present meta-analysis was to evaluate whether the use of colchicine in patients with coronary artery disease with diabetes was associated with a higher magnitude of benefits compared to patients with coronary artery disease without diabetes.
Methods: Electronic databases were searched through June 2020 to identify randomized clinical trials using colchicine in patients with coronary artery disease.
A 3-dimensional, robust, and sustained myocardial restoration by means of tissue engineering remains an experimental approach. Prolific protocols have been developed and tested in small and large animals, but, as clinical cardiac surgeons, we have not arrived at the privilege of utilizing any of them in our clinical practice. The question arises as to why this is.
View Article and Find Full Text PDFBackground Polyvascular atherosclerotic disease is associated with an increased risk of future cardiovascular events. Intensive lipid-lowering therapy (ILT) may mitigate this risk. The aims of this study-level meta-analysis were to examine the effects of ILT in patients with polyvascular disease and whether baseline low-density lipoprotein cholesterol (LDL-C) may determine the level of benefit.
View Article and Find Full Text PDFBackground: Although several studies revealed that the Cor-knot automated fastener (LSI Solutions, Victor, NY) reduces aortic cross-clamp and cardiopulmonary bypass times, the influence of the device on postoperative morbidity and mortality still needs to be evaluated. The aim of this study was to verify the hypothesis that the use of the Cor-knot device for heart valve surgery reduces aortic cross-clamp and cardiopulmonary bypass times, and this time saving translates into reduced morbidity and mortality.
Methods: Retrospective cohort studies and randomized controlled trials reporting on the use of the automated fastener vs hand-tied knots were reviewed.
Transcatheter treatment of functional mitral valve regurgitation.
Trends Cardiovasc Med
November 2021
Functional mitral regurgitation is a clinical entity with increasing prevalence and significant impact on morbidity and mortality. Because of the unsatisfactory results of medical therapy and high perioperative risk resulting in low referral/high denial rates for surgical treatment, benefits of which still remain controversial, novel minimally invasive transcatheter techniques are under development. Herein, in the present review, we discuss the recent progress in the emerging field of catheter-based techniques for functional mitral regurgitation.
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