We develop a general quantum theory for reactive collisions involving power-law potentials (-1/r(n)) valid from the ultracold up to the high-temperature limit. Our quantum defect framework extends the conventional capture models to include the nonuniversal case when the short-range reaction probability P(re)<1. We present explicit analytical formulas as well as numerical studies for the van der Waals (n=6) and polarization (n=4) potentials.
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