Matrix metaloproteinase-2 and -9 serum levels as potential markers of intraperitoneal adhesions.

Objective: To assess the value of matrix metalloproteinases-2 (MMP-2) and -9 (MMP-9) as prognostic serum markers for intraperitoneal adhesions.

Background: Postoperative adhesions are associated with serious complications responsible for increased patient's morbidity.

Methods: Forty-eight rabbits were used and randomized into groups A, B, C, and D.

Local excision for early rectal cancer in the era of neoadjuvant strategies.

Advanced staging methodology and the evolution of new neoadjuvant therapeutic strategies have changed the management of rectal cancer. In selected cases, such as elderly patients or those denying a stoma, local excision of early rectal cancer should be considered an option in the spectrum of a multimodality treatment.