Latitudinal Clines in Climate and Sleep Patterns Shape Disease Outcomes in Infected by .

Major latitudinal clines have been observed in , a human commensal that originated in tropical Africa and has subsequently dispersed globally to colonize temperate habitats. However, despite the crucial role pathogens play in species distribution, our understanding of how geographical factors influence disease susceptibility remains limited. This investigation explored the effects of latitudinal clines and biomes on disease resistance using the common fly pathogen and 43 global populations.