Human skeletal muscle: transition between fast and slow fibre types.

Human skeletal muscles consist of different fibre types: slow fibres (slow twitch or type I) containing the myosin heavy chain isoform (MHC)-I and fast fibres (fast twitch or type II) containing MHC-IIa (type IIA) or MHC-IId (type IID). The following order of decreasing kinetics is known: type IID > type IIA >> type I. This order is especially based on the kinetics of stretch activation, which is the most discriminative property among fibre types.