Publications by authors named "Michaela Romanovova"
Dalton Trans
September 2023
Article Synopsis
- Two types of half-sandwich complexes featuring a thiadiazole-based ligand have been synthesized and characterized, showing hydrolytic stability and the ability to oxidize NADH.
- Iridium complexes (2 and 4) demonstrated higher catalytic activity and greater lipophilicity compared to ruthenium complexes (1 and 3), while also showing minimal interaction with reduced glutathione.
- Biological analyses revealed that complexes 2 and 4 were selective against human fibroblasts and showed moderate inhibition of cancer cell activity, particularly complex 4, indicating potential for development as new anticancer drugs, especially for cisplatin-resistant tumors.
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