Publications by authors named "Michaela Matyskova-Kubisova"

Article Synopsis
  • Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder often leading to end-stage renal disease, and this study reviews native nephrectomy (NN) practices over 25 years at a transplant center.
  • A total of 89 out of 152 ADPKD patients who underwent kidney transplantation (KT) also had NN, with most NN being unilateral and planned surgeries showing better outcomes than acute ones.
  • The findings highlight the importance of careful planning and patient-specific strategies in NN for ADPKD due to increased complications associated with acute surgeries.
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Article Synopsis
  • * Only 3.2% of patients required hospitalization, and most experienced stable kidney function post-infection, with minimal complications.
  • * The findings indicate that early molnupiravir treatment and adjusting immunosuppression can lead to positive outcomes, preserving kidney graft function without graft rejection.
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Human polyomaviruses such as JC polyomavirus and BK polyomavirus have long been well known pathogens of immunocompromised patients. Several new members of this viral family have been described during the last decade. Human polyomavirus 9 seems to be a novel pathogen of transplanted patients according to some studies.

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The well-described disparity between the need for and the supply of organs suitable for transplant is growing. Because of this disparity, mortality of patients listed for transplant is increasing. Donors who die of intoxication (including victims of methanol poisoning) represent less than 1% of suitable donors and might be used to increase the supply of organs.

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