Primary cytomegalovirus (CMV) infection in pregnancy: Diagnostic value of CMV PCR in saliva compared to urine at birth.

Background: Due to its ease of collection saliva was recently recommended as the preferred specimen, not only for screening, but also for diagnosis of congenital cytomegalovirus (CMV) infection.

Objective: To compare the diagnostic performance of saliva PCR to urine PCR in infants born to mothers with primary CMV infection during pregnancy.

Study Design: We retrospectively analyzed available data of infants tested for CMV DNA in urine and saliva at birth.

Roche AMPLICOR human papilloma virus (HPV) and LINEAR ARRAY HPV tests will profit from automated DNA extraction.

Background: Persistent infection with high risk human papillomavirus (HR-HPV) types is at the origin of cervical cancer in women and HPV-genotyping is considered to be a valuable tool for risk stratification. Its diagnostic relevance will further increase in the context of HPV vaccination which covers the HR-HPV types 16 and 18 only. For rapid screening and genotyping the commercial Roche AMPLICOR and the Roche LINEAR ARRAY (LA) HPV PCR tests are available.