Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism.

A 6-month-old kitten, male, domestic shorthair cat was presented with dwarfism, ocular and nasal discharge, and infestation. Congenital hyposomatotropism was diagnosed on the basis of serum level of insulin-like growth factor-1 (IGF-I). The cat was treated with human recombinant growth hormone for 9 weeks.

Novel approach of dermatophytosis eradication in shelters: effect of Pythium oligandrum on Microsporum canis in FIV or FeLV positive cats.

Background: Shelters and similar facilities with a high concentration and fluctuation of animals often have problems with various infections, which are usually difficult to solve in such environments and are very expensive to treat. This study investigated the eradication of Microsporum canis, the widespread cause of zoonotic dermatophytosis in shelters, even in immunosuppressed feline leukaemia virus or feline immunodeficiency virus positive cats.

Results: Our study showed the increased effectiveness of an alternative topical therapy for affected animals using the mycoparasitic fungus Pythium oligandrum, which is gentler and cheaper than the standard systemic treatment with itraconazole, and which can also be easily used as a preventative treatment.

Inorganic Salts of -phenylbiguanidium(1+)-Novel Family with Promising Representatives for Nonlinear Optics.

Seven inorganic salts containing -phenylbiguanide as a prospective organic molecular carrier of nonlinear optical properties were prepared and studied within our research of novel hydrogen-bonded materials for nonlinear optics (NLO). All seven salts, namely -phenylbiguanidium(1+) nitrate (2/), -phenylbiguanidium(1+) perchlorate (-1), -phenylbiguanidium(1+) hydrogen carbonate (2/), bis(-phenylbiguanidium(1+)) sulfate (2), bis(-phenylbiguanidium(1+)) hydrogen phosphate sesquihydrate (-1), bis(-phenylbiguanidium(1+)) phosphite (2), and bis(-phenylbiguanidium(1+)) phosphite dihydrate (2/), were characterised by X-ray diffraction (powder and single-crystal X-ray diffraction) and by vibrational spectroscopy (FTIR and Raman). Two salts with non-centrosymmetric crystal structures-bis(-phenylbiguanidium(1+)) sulfate and bis(-phenylbiguanidium(1+)) phosphite-were further studied to examine their linear and nonlinear optical properties using experimental and computational methods.

Thermoreversible magnetic nanochains.

The reversible organization of nanomagnets into highly anisotropic assemblies is of considerable interest for many applications, including theragnostic strategies in vivo. The current preparation strategies lead to structures that are not stable without the permanent presence of an applied magnetic field (MF); otherwise, irreversible assemblies are produced with moderate shape anisotropy at nanoscales. Here, we present a new approach based on the thermoreversible Diels-Alder reaction in the presence of an external MF that enables the assembly of single-domain nanomagnets into narrow chains with lengths of several micrometers.

Proton-Gradient-Driven Oriented Motion of Nanodiamonds Grafted to Graphene by Dynamic Covalent Bonds.

Manipulating nanoscopic objects by external stimuli is the cornerstone of nanoscience. Here, we report the implementation of dynamic covalent chemistry in the reversible binding and directional motion of fluorescent nanodiamond particles at a functionalized graphene surface via imine linkages. The dynamic connections allow for controlling the formation and rupture of these linkages by external stimuli.

Mammalian enamel maturation: Crystallographic changes prior to tooth eruption.

Using the distal molar of a minipig as a model, we studied changes in the microstructural characteristics of apatite crystallites during enamel maturation (16-23 months of postnatal age), and their effects upon the mechanical properties of the enamel coat. The slow rate of tooth development in a pig model enabled us to reveal essential heterochronies in particular components of the maturation process. The maturation changes began along the enamel-dentine junction (EDJ) of the trigonid, spreading subsequently to the outer layers of the enamel coat to appear at the surface zone with a 2-month delay.

Antifungal effects of the biological agent Pythium oligandrum observed in vitro.

Objectives Dermatophytosis, commonly known as ringworm, is a superficial fungal skin disease and zoonosis. Pythium oligandrum is a micromycete with mycoparasitic properties that is used in agriculture to control fungal infections on plants. Formulations containing P oligandrum were also developed for the treatment of dermatophytoses, but only a small number of case studies have been published.

Mobility and attenuation of arsenic in sulfide-rich mining wastes from the Czech Republic.

The mineralogical composition of mining wastes deposited in countless dumps around the world is the key factor that controls retention and release of pollutants. Here we report a multi-method data set combining mineralogical (X-ray diffraction, electron microprobe and Raman microspectrometry) and geochemical (sequential extraction and pore water analysis) methods to resolve As mobility in two 50-years-old mining waste dumps. Originally, all of the As in the mining wastes selected for the study was present as arsenopyrite and with time it has been replaced by secondary As phases.

N-[Amino(imino)methyl]uronium tetrafluoroborate.

In the title compound, C(2)H(7)N(4)O(+)·BF(4) (-), inter-molecular N-H⋯O hydrogen bonds connect the cations into chains parallel to the c axis, with graph-set motif C(4). These chains are in turn connected into a three-dimensional network by inter-molecular N-H⋯F hydrogen bonds. The B-F distances distances in the anion are not equal.

Mixed crystals of 2-carbamoylguanidinium with hydrogen fluorophosphonate and hydrogen phosphite in the ratios 1:0, 0.76 (2):0.24 (2) and 0.115 (7):0.885 (7).

The title compounds, 2-carbamoylguanidinium hydrogen fluorophosphonate, C(2)H(7)N(4)O(+)·HFO(3)P(-), (I), 2-carbamoylguanidinium-hydrogen fluorophosphonate-hydrogen phosphite (1/0.76/0.24), C(2)H(7)N(4)O(+)·0.

Two polymorphs of bis(2-carbamoylguanidinium) fluorophosphonate dihydrate.

Two polymorphs of bis(2-carbamoylguanidinium) fluorophosphonate dihydrate, 2C(2)H(7)N(4)O(+)·FO(3)P(2-)·2H(2)O, are presented. Polymorph (I), crystallizing in the space group Pnma, is slightly less densely packed than polymorph (II), which crystallizes in Pbca. In (I), the fluorophosphonate anion is situated on a crystallographic mirror plane and the O atom of the water molecule is disordered over two positions, in contrast with its H atoms.

Tris(2-carbamoylguanidinium) hydrogen fluoro-phospho-nate fluoro-phospho-nate monohydrate.

The title structure, 3C(2)H(7)N(4)O(+)·HFPO(3) (-)·FPO(3) (2-)·H(2)O, contains three independent 2-carbamoylguanidinium cations, one fluoro-phospho-nate, one hydrogen fluoro-phospho-nate and one water mol-ecule. There are three different layers in the structure that are nearly perpendicular to the c axis. Each layer contains a cation and the layers differ by the respective presence of the water mol-ecule, the hydrogen fluoro-phospho-nate and fluoro-phospho-nate anions.

1,1-Dimethyl-biguanidium(2+) dinitrate.

In the crystal structure of the title compound, C(4)H(13)N(5) (2+)·2NO(3) (-), the main inter-molecular inter-actions are the N-H⋯O hydrogen bonds between the cationic amino groups and the O atoms of the nitrate ions. All amino H atoms and nitrate O atoms are involved in the three-dimensional hydrogen-bond network. There are two graph-set motifs R(2) (2)(8), which include the amino groups connected to the N atoms in the biguanide 3-, 4- and 5-positions, and the O atoms of a nitrate ion.