Publications by authors named "Michael Zumwalt"

The Table in the article "Latex Hypersensitivity to Injection Devices for Biologic Therapies in Psoriasis Patients" (Cutis. 2018;102:116-118.) incorrectly stated that guselkumab contains latex.

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Use of dermoscopy and detection algorithms by primary care physicians can enhance assessment of clinically suspicious lesions compared with that of naked eye examinations.

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An allergic reaction provoked by reexposure to an allergen or antigen is known as a type I or immediate hypersensitivity reaction. Latex allergy is a common cause of type I hypersensitivity reactions. Allergic responses to latex in psoriasis patients receiving frequent injections with biologic agents are not commonly reported in the literature.

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A single radial suture is required for a corneal or limbal incision that does not seal despite stromal hydration. In the traditional technique for placing this suture, the needle enters from the corneal side of the limbal incision and exits toward the scleral side and the suture is usually tied with a 3-1-1 surgical knot. We present an improved suturing technique in which the needle path is reversed.

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A rapid, simple, highly sensitive procedure for the simultaneous analysis of bromazepam, alprazolam, clonazepam, lorazepam, oxazepam, diazepam, midazolam, flurazepam, flunitrazepam, nordiazepam, triazolam, temazepam, nitrazepam, and chlordiazepoxide in oral fluid is described, using liquid chromatography coupled to a triple quadrupole mass spectrometer in positive electrospray mode. Benzodiazepines in oral fluid samples (1 mL) were analyzed using the Quantisal collection device, quantified using solid-phase extraction, and detected using liquid chromatography with tandem mass spectrometric detection. For confirmation, two transitions were monitored and one ion ratio determined, which was within 20% of the ratio for known calibration standards.

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Exact masses of monoisotopic ions, and the relative isotopic abundances (RIAs) of ions greater in mass by 1 and 2 Da than the monoisotopic ion, are independent and complementary physical properties useful for distinguishing among elemental compositions of ions possible for a given nominal mass. Using these properties to determine elemental compositions of product ions and neutral losses increases the masses of precursor ions for which unique compositions can be determined. Compositions of the precursor ion, product ion, and neutral loss aid mass spectral interpretation and guide modest chemical literature searches for candidate standards to be obtained for confirmation of tentative compound identifications.

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