Publications by authors named "Michael Vernizzi"
Article Synopsis
- The study utilizes fluorescence lifetime imaging microscopy (FLIM) to investigate how nanoencapsulated liposomal all-trans retinoic acid (ATRA) interacts with liposomal membranes, utilizing ATRA's natural fluorescence for signal detection.
- The method is validated through additional techniques like small-angle X-ray scattering (SAXS) and nano-differential scanning calorimetry (NanoDSC), confirming ATRA's location and impact on membrane structure.
- Results highlight the effectiveness of Phasor-FLIM in analyzing the nanoscale organization of fluorescent drugs, emphasizing the significance of advanced imaging in enhancing drug delivery systems.
