A unique enzootic focus of Mycobacterium bovis in free-ranging deer was identified in Michigan, leading to human cases linked to these deer between 1994 and 2022; four new cases were confirmed using genomic epidemiology.
Genetic analysis showed a close connection between human and animal strains, with some cases having minimal genetic differences from deer and cattle isolates.
Ongoing transmission of M. bovis from deer to humans and cattle poses a public health risk, prompting the need for future studies and a One Health approach to tackle TB transmission effectively.
Objective: To determine prevalence of tuberculosis caused by infection with Mycobacterium bovis in cervids on privately owned ranches in northeastern lower Michigan.