Publications by authors named "Michael T Padomek"
The Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America "Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship" recommend the use of computer-based surveillance programs for efficient and thorough identification of potential interventions as part of an antimicrobial stewardship program (ASP). This retrospective study examined the benefit of utilizing a clinical surveillance software program to help guide antimicrobial therapy in an inpatient setting, in a small community hospital, without a formal ASP. The electronic health record (EHR) was used to retrieve documentations for the following types of antibiotic interventions: culture surveillance, duplicate therapy, duration of therapy and renal dose adjustments.
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- The study evaluated six different gentamicin dosing regimens for premature and full-term neonates in a neonatal intensive care unit.
- The research found that specific dosing strategies led to peak gentamicin concentrations in the target range more frequently for different gestational age groups.
- Overall, gentamicin 3.5 mg/kg every 36 hours was the most effective for neonates aged 30-34 weeks, while 3.5 mg/kg every 24 hours was optimal for those 35 weeks or older, with no significant differences in trough levels across age groups.