Comput Methods Programs Biomed
March 2021
Background And Objective: Glaucoma is currently a major cause for irreversible blindness worldwide. A risk factor and the only therapeutic control parameter is the intraocular pressure (IOP). The IOP is determined with tonometers, whose measurements are inevitably influenced by the geometry of the eye.
View Article and Find Full Text PDFPurpose: Glaucoma is the world's most common cause of irreversible blindness, which makes early diagnosis, with the goal of preserving vision, essential. The current medical intervention is to reduce intraocular pressure (IOP) to slow down progression of the disease. The main goal of this study was to test a novel handheld acoustic self-tonometer on humans.
View Article and Find Full Text PDFSensors (Basel)
August 2019
In order to fix a fracture in osteosynthesis, it is necessary to attach screws bicortically to the bone. The length of the screws must be selected correctly in 1-mm increments: otherwise, injury to the surrounding tissue structure or insufficient fixation will result. The drill channel length can only be determined preoperatively to a limited extent and with insufficient accuracy and is therefore determined intraoperatively with a mechanical caliper gauge.
View Article and Find Full Text PDFMotivation Glaucoma is currently the most common irreversible cause of blindness worldwide. A significant risk factor is an individually increased intraocular pressure (IOP). A precise measurement method is needed to determine the IOP in order to support the diagnosis of the disease and to monitor the outcome of the IOP reduction as a medical intervention.
View Article and Find Full Text PDFPhycoerythrobilin (PEB) is an open-chain tetrapyrrole derived from heme and plays an important role as light-harvesting pigment in the phycobiliproteins of cyanobacteria and red algae. Furthermore, PEB can also function as an antioxidant with potential use as a natural acid stable food colorant. PEB is not commercially available and large, pure quantities can only be obtained by laborious methanolysis of red algae followed by liquid chromatography.
View Article and Find Full Text PDFPurpose: An accurate measurement of intraocular pressure (IOP) is still essential for detecting, following-up, and treating glaucoma. The objective of the interdisciplinary project GlauPhon was to prove a new noncontact tonometry principle that analyzes the acoustic oscillation of the eye.
Method: Three enucleated porcine eyes were infused via the optic nerve with a saline solution.