Objective: To review the pharmacology, safety, and efficacy of the prokinetic agents metoclopramide and erythromycin in children.
Data Sources: English-language literature was accessed using MEDLINE (1970-June 2004) with metoclopramide, erythromycin, macrolides, gastroesophageal reflux, and gastrointestinal motility as the search terms.
Study Selection And Data Extraction: Abstracts and original research articles were included.