Publications by authors named "Michael S Goligorksy"
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Synopsis of recent research by authors named "Michael S Goligorksy"
- Michael S Goligorksy's research primarily focuses on renal injury mechanisms, particularly the roles of High-Mobility Group Box 1 (HMGB1) in renal pathophysiology and the investigation of endogenous repair processes post-injury.
- His work has identified the deacetylation of HMGB1 by Sirtuin1 as a key regulatory mechanism in modulating inflammatory signaling pathways during renal stress, showcasing the intricate interplay between cellular damage and immune responses.
- Additionally, Goligorksy has explored cellular behaviors such as elongation during vasculogenesis, contributing to a deeper understanding of the vascular development process and its relevance to kidney function and repair.