Publications by authors named "Michael Rudoni"
Article Synopsis
- The study investigates the effectiveness of two weight-based dosing strategies for atracurium in obese patients with acute respiratory distress syndrome (ARDS) during the COVID pandemic, focusing on oxygenation changes after treatment.
- It compares the outcomes of patients receiving atracurium based on actual body weight (ABW) versus ideal body weight (IBW), finding no significant difference in oxygenation improvement after 48 hours despite different dosing amounts.
- The results indicated higher atracurium doses in the ABW group, but no differences in mortality rates or days free from ICU or ventilator support, suggesting both dosing methods may be equally viable for this patient population.
Background: Atrial fibrillation (AF) and atrial flutter (AFL) are frequently seen in critically ill sepsis patients and are associated with poor outcomes. There is a need for further research, however, studies are limited due to challenges in identifying patient cohorts. Administrative data using the International Classification of Diseases, Tenth Revision (ICD-10) are routinely used for identifying disease cohorts in large datasets.
View Article and Find Full Text PDFLung transplant recipients are at an increased risk for Clostridioides difficile infection (CDI), and those who develop CDI post-transplant can have worsened outcomes including graft failure and death. We sought to describe the efficacy and safety of primary CDI prophylaxis with oral vancomycin among 86 adult lung transplant recipients. Overall, we observed a 9.
View Article and Find Full Text PDFBackground: Essential to the coagulation pathway, vitamin K (phytonadione) is used to correct clotting factor deficiencies and for reversal of warfarin-induced bleeding. In practice, high-dose intravenous (IV) vitamin K is often used, despite limited evidence supporting repeated dosing.
Objective: This study sought to characterize differences in responders and nonresponders to high-dose vitamin K to guide dosing strategies.
Objectives: To assess the evidence and discuss the risks and clinical relevance of ketamine for the treatment of various disease states impacting the adult critically ill population.
Data Sources: A literature review was performed using PubMed evaluating primary literature published until August 2018.
Study Selection: Case reports, observational studies (cohort, case-control), and randomized controlled trials involving patients 18 years and older in a nonperioperative setting using either IV or intramuscular ketamine were included for analysis.