Childhood maltreatment and migraine (part I). Prevalence and adult revictimization: a multicenter headache clinic survey.

Objectives: To examine the prevalence of childhood maltreatment and adult revictimization in migraineurs and the association with sociodemographic factors, depression and anxiety.

Background: Population and practice-based studies have demonstrated an association of childhood abuse and headache in adults, although further details on headache diagnoses, characteristics, and comorbid conditions are lacking. There are mounting data suggesting substantial impact of early maltreatment on adult physical and mental health.

Childhood maltreatment and migraine (part II). Emotional abuse as a risk factor for headache chronification.

Objectives: To assess in a headache clinic population the relationship of childhood abuse and neglect with migraine characteristics, including type, frequency, disability, allodynia, and age of migraine onset.

Background: Childhood maltreatment is highly prevalent and has been associated with recurrent headache. Maltreatment is associated with many of the same risk factors for migraine chronification, including depression and anxiety, female sex, substance abuse, and obesity.

Childhood maltreatment and migraine (part III). Association with comorbid pain conditions.

Objective: To evaluate in a headache clinic population the relationship of childhood maltreatment on the prevalence of pain conditions comorbid with migraine.

Background: Childhood maltreatment is highly prevalent and has been frequently associated with recurrent headache. The relationship of maltreatment and pain has, however, been a subject of some debate.

Allodynia in migraine: association with comorbid pain conditions.

Background: Cutaneous allodynia (CA) in migraine is a clinical manifestation of central nervous system sensitization. Several chronic pain syndromes and mood disorders are comorbid with migraine. In this study we examine the relationship of migraine-associated CA with these comorbid conditions.

Depression and anxiety: effect on the migraine-obesity relationship.

Objective: To discern the effects of depression and anxiety on the migraine-obesity relationship.

Background: Migraine and obesity are highly prevalent conditions and are both independently linked to psychiatric conditions, mainly depression and anxiety.

Methods: Data are from an ongoing cross-sectional multicenter study on comorbid conditions in clinic patients seeking treatment for headache.