Synopsis of recent research by authors named "Michael Pritt"
- Michael Pritt's recent research primarily focuses on evaluating the efficacy and safety of novel biomarkers in toxicological studies, particularly related to drug-induced injuries in various organ systems of rodents.
- His studies have demonstrated that new biomarkers, such as skeletal troponin I and fatty acid binding protein 3, significantly outperform traditional biomarkers like AST and CK in detecting skeletal muscle damage, as well as cardiac injuries.
- Pritt's work also emphasizes the importance of strain-dependent effects in toxicology, showcasing how different rat strains may react differently to compound treatments, which is critical for understanding drug toxicity and improving preclinical assessment protocols.