Publications by authors named "Michael Pinkas"
Article Synopsis
- * Testing for CTCs is becoming important for deciding treatment plans and can show how well a treatment is working over time.
- * The study shares experiences with CTC testing in various cancer patients, highlighting its usefulness in treating conditions like breast, colorectal, prostate, and lung cancer.
Circulating tumor cells in different stages of colorectal cancer.
Folia Histochem Cytobiol
March 2018
Introduction: Liquid biopsies are noninvasive tests using blood or body fluids to detect circulating tumor cells (CTCs) or the products of tumor cells, such as fragments of nucleic acids or proteins that are shed into biological fluids from primary tumor or its metastates. The analysis of published clinical studies provides coherent evidence that the presence of CTCs detected in peripheral blood is a strong prognostic factor in patients with colorectal carcinoma (CRC). The aim of the study was to implement size-based separation protocol of CTCs in CRC patients.
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- The study aimed to find cancer cells in the blood of ovarian cancer patients using a new method called MetaCell, which sorts these cells by their size.
- After capturing the cells, they used a special microscope to look at them closely and do more tests on their DNA and RNA.
- The researchers found that certain genes were present in higher amounts in the cancer cells compared to the normal blood, which could help identify ovarian cancer more accurately than using just one gene test.
Delayed diagnosis of ovarian cancer (OC) is usually a cause of its high mortality. OC counts for one of the most aggressive gynecological malignancies. Noninvasive biomarkers may be used to help with diagnostic and treatment decisions in OC management.
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