Publications by authors named "Michael P O'Neil"
Article Synopsis
- Pulsatile perfusion during cardiopulmonary bypass (CPB) may enhance microcirculation compared to traditional nonpulsatile methods, as evidenced by a study involving high-risk cardiac patients.
- The study measured microcirculatory characteristics and tissue oxygen saturation at various time points during and after CPB, revealing that the pulsatile group maintained better blood flow and perfusion.
- Overall, the findings suggest that pulsatile flow can lead to better recovery of microvascular function and potentially reduce complications related to systemic inflammation and reperfusion injury.
Background And Objectives: Perfluorodecalin (PFD) has previously been shown to rapidly dissipate the opaque, white micro-bubble layer formed after exposure of tattoos to Q-switched lasers [1]. The current pilot study was conducted to qualitatively determine if the use of a transparent PFD-infused silicone patch would result in more rapid clearance of tattoos than conventional through-air techniques.
Materials And Methods: Black or dark blue tattoos were divided into two halves in a single-site IRB-approved study with 17 subjects with Fitzpatrick skin types I-III.
Background: Controversy exists regarding the optimal perfusion modality during cardiopulmonary bypass (CPB). Here we compare the effects of pulsatile versus nonpulsatile perfusion on microvascular blood flow during and after CPB.
Methods: High-risk cardiac surgical patients were randomly assigned to have pulsatile (n=10) or nonpulsatile (n=10) flow during CPB.