Publications by authors named "Michael P Khairallah"
Article Synopsis
- The calvaria, or upper part of the skull, develops from mesenchyme around the brain, with specific regions (like supra-orbital mesenchyme) promoting bone growth while others (early migrating mesenchyme) do not.
- Researchers discovered Lmx1b, a gene that acts as an anti-osteogenic factor in early migrating mesenchyme, helping to differentiate areas with varying capacities for bone development.
- Altering the expression of Lmx1b can lead to abnormal bone growth and conditions like craniosynostosis, highlighting its crucial role in the proper formation and organization of the skull.
