Publications by authors named "Michael P Bonk"
Septicemia After a Dog Bite: The Case of a Usual Suspect Transmitting an Unusual Organism.
Clin Pract Cases Emerg Med
August 2024
Article Synopsis
- This text discusses a rare case of antibiotic-resistant septicemia linked to canine bites in a 70-year-old man with a history of lymphoma, who showed severe symptoms and multiorgan failure after the incident.* -
- The case highlights concerns about the transmission of infections from dogs to humans, particularly from oral microbiome bacteria that can be resistant to common antibiotics.* -
- The conclusion emphasizes the importance of considering these infections in patients with severe sepsis after dog bites, along with the need for thorough medical histories and appropriate antibiotic selection to improve patient outcomes.*
BACKGROUNDThe ABO histo-blood group is defined by carbohydrate modifications and is associated with risk for multiple diseases, including acute respiratory distress syndrome (ARDS). We hypothesized that genetically determined blood subtype A1 is associated with increased risk of ARDS and markers of microvascular dysfunction and coagulation.METHODSWe conducted analyses in 3 cohorts of critically ill trauma and sepsis patients (n = 3710) genotyped on genome-wide platforms to determine the association of the A1 blood type genotype with ARDS risk.
View Article and Find Full Text PDFCystic fibrosis (CF) is the most common life-limiting genetic disease in Caucasian patients. Continued advances have led to improved survival, and adults with CF now outnumber children. As our understanding of the disease improves, new therapies have emerged that improve the basic defect, enabling patient-specific treatment and improved outcomes.
View Article and Find Full Text PDFPurpose: The objective of this study is to describe the relationship between two quantitative muscle ultrasound measures, the rectus femoris cross-sectional area (RF-CSA) and quadriceps muscle thickness, with volitional measures of strength and function in critically ill patients with sepsis.
Materials And Methods: We performed a prospective study of patients admitted to a medical ICU with sepsis and shock or respiratory failure. We examined the association of two ultrasound measurements - the RF-CSA and quadriceps muscle thickness - with strength and function at day 7.